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In this work, a new and green strategy for functional hyper\u2010crosslinked adsorption resin based on Friedel\u2013Crafts reaction of pendant vinyl groups in divinylbenzene with anhydrous ethanol and acrylamide grafting polymerization was developed, and the obtained HCREt\u2010AM resin had excellent performance on chlorogenic acid separation from <jats:italic>Eucommia ulmoides Oliver<\/jats:italic> leaf extract. Adsorption isotherm and kinetics study showed the adsorption process fitted by Langmuir adsorption isotherm and pseudo\u2010second\u2010order kinetic equation. The dynamic saturated adsorption capacity of 88.0 mg\u00b7g<jats:sup>\u22121<\/jats:sup> was obtained, and chlorogenic acid content was raised from 7.91% to 48.27%. The pH\u2010controlled ionization of chlorogenic acid determined the adsorption process, and \u03c0\u2010\u03c0 stacking, hydrophobic interactions, hydrogen bonding, and electrostatic interactions are the main adsorption mechanisms.<\/jats:p>","DOI":"10.1002\/jssc.70256","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T03:59:41Z","timestamp":1757390381000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Green Synthetic Amide\u2010Modified Hyper\u2010Cross\u2010Linked Adsorption Resin for Efficiently Separating Chlorogenic Acid From <i>Eucommia ulmoides<\/i> Extracts"],"prefix":"10.1002","volume":"48","author":[{"given":"Xuefang","family":"Chen","sequence":"first","affiliation":[{"name":"Guangzhou Institute of Energy Conversion CAS Key Laboratory of Renewable Energy Chinese Academy of Sciences  Guangzhou People's Republic of China"},{"name":"School of Energy Science and 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