{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T21:23:15Z","timestamp":1787174595766,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Separation Science"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This work addresses the challenge of imparting molecular selectivity to metal\u2010organic frameworks (MOFs) by developing a molecularly imprinted polymer based on ZIF\u201090 (MI\u2010ZIF). Starch was used as a green and multifunctional auxiliary polymer during a room\u2010temperature preparation of MI\u2010ZIF with baicalin as the template. This strategy leverages the hydroxyl groups of starch to orchestrate the formation of specific recognition cavities within the ZIF\u201090 framework. The well prepared MI\u2010ZIF exhibited high adsorption capacity and good specificity, with an imprinting factor (IF) of 4.1. The MI\u2010ZIF was used to enrich baicalin from complex matrices such as plant extracts and serum samples. It achieved a high adsorption rate of 93.2% for baicalin from a\n                    <jats:italic>Scutellaria baicalensis<\/jats:italic>\n                    Georgi (SBG) root extract, increasing the baicalin purity from 19.7% to 71.3%. As a solid\u2010phase extraction sorbent for the analysis of serum samples, this method showed high sensitivity with a detection limit of 0.9\u00a0ng mL\n                    <jats:sup>\u22121<\/jats:sup>\n                    and recoveries in the range of 78.2%\u201397.2%. The results indicate that the MI\u2010ZIF can significantly improve the enrichment efficiency and detection sensitivity of baicalin, providing an efficient and reliable technical means to solve the problems of enrichment, separation, and trace detection of flavonoid compounds in complex samples.\n                  <\/jats:p>","DOI":"10.1002\/jssc.70420","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T12:16:04Z","timestamp":1776428164000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Starch\u2010Assisted Molecularly Imprinted ZIF\u201090 for Enhanced Extraction of Baicalin Followed by Chromatographic Determination"],"prefix":"10.1002","volume":"49","author":[{"given":"Wen\u2010Zhi","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Pharmacology Xiangya School of Pharmaceutical Sciences Central South University  Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao\u2010Nan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Xiangya School of Pharmaceutical Sciences Central South University  Changsha Hunan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Xiangya School of Pharmaceutical Sciences Central South University  Changsha Hunan China"},{"name":"Hunan Provincial Key Laboratory of Cardiovascular Research Central South University  Changsha Hunan 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