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Patterns of PTSD symptom change are not well understood. Thus, the current study was designed to categorize and investigate potential predictors of symptom trajectories in patients with PTSD. The sample comprised 2,237 VA patients who were diagnosed with PTSD in 2013 and completed at least 4 PTSD Checklist (PCL) assessments over 12 weeks. Latent trajectory analysis was used to identify latent classes of patients based on PCL scores. Based on model fit indices, 3 trajectories were identified. Compared to patients in the mild\u2010improving trajectory (21.9%), those in the severe\u2010stable trajectory (34.3%) were more likely to be male, relative risk ratio (RRR) = 1.48, 95% CI [1.08, 2.02]; non\u2010White, RRR = 1.77, 95% CI [1.33, 2.35]; Hispanic, RRR = 2.07, 95% CI [1.40, 3.04]; and have comorbid depression, RRR = 1.58, 95% CI [1.25, 1.99]. Compared to patients in the moderate\u2010improving trajectory (43.8%), those in the severe\u2010stable trajectory were more likely to have sleep disorders, RRR = 1.25, 95% CI [1.01, 1.55]. Our findings suggest that male veterans, minority veterans, and veterans with certain comorbid conditions may be less likely to achieve improved PTSD symptoms. Targeted efforts are needed to improve outcomes for PTSD patients on nonremitting trajectories and to improve the consistency of PTSD assessment across the VA health care system.<\/jats:p>","DOI":"10.1002\/jts.22156","type":"journal-article","created":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T05:23:24Z","timestamp":1484889804000},"page":"45-53","source":"Crossref","is-referenced-by-count":30,"title":["Predictors of PTSD Symptom Change Among Outpatients in the U.S. Department of Veterans Affairs Health Care System"],"prefix":"10.1002","volume":"30","author":[{"given":"Rebecca K.","family":"Sripada","sequence":"first","affiliation":[{"name":"Veterans Affairs Center for Clinical Management Research Health Services Research and Development  Ann Arbor Michigan USA"},{"name":"Veterans Affairs Ann Arbor Health Care System  Ann Arbor Michigan USA"},{"name":"Department of Psychiatry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul N.","family":"Pfeiffer","sequence":"additional","affiliation":[{"name":"Veterans Affairs Center for Clinical Management Research Health Services Research and Development  Ann Arbor Michigan USA"},{"name":"Veterans Affairs Ann Arbor Health Care System  Ann Arbor Michigan USA"},{"name":"Department of Psychiatry University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Rampton","sequence":"additional","affiliation":[{"name":"Veterans Affairs Center for Clinical Management Research Health Services Research and Development  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dara","family":"Ganoczy","sequence":"additional","affiliation":[{"name":"Veterans Affairs Center for Clinical Management Research Health Services Research and Development  Ann Arbor Michigan USA"},{"name":"Veterans Affairs Ann Arbor Health Care System  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila A. 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