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Sleep disorders may lead to avoidance of effortful tasks and cognitive performance deficits. We explored whether sleep disorders, as assessed by polysomnography, were consistently associated with treatment response in combination with other factors. This study included 32 U.S. veterans who were examined both before and after CPT for combat\u2010related PTSD. We employed a novel, case\u2010comparative technique, fuzzy set qualitative comparative analysis (fsQCA), to identify combinations of fuzzy and crisp factors (recipes) that achieve a clinically significant outcome. Approximately one\u2010quarter of cases experiencing clinically significant change were either (a) Vietnam era veterans without sedating medications, moderate sleep disordered breathing, and severe depression; or (b) non\u2013Vietnam era veterans with sedating medications and without severe periodic limb movements (or significant periodic limb movement arousals). Recipes involving the absence of the relevant sleep disorder were associated with the highest coverage values. These results using fsQCA (a) provide valuable information about the heterogeneity of CPT response and (b) suggest that sleep disorders are important factors to consider in theoretical discussions of who responds to CPT for PTSD.<\/jats:p>","DOI":"10.1002\/jts.22233","type":"journal-article","created":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T13:28:12Z","timestamp":1511270892000},"page":"635-645","source":"Crossref","is-referenced-by-count":11,"title":["The Effect of Sleep Disorders, Sedating Medications, and Depression on Cognitive Processing Therapy Outcomes: A Fuzzy Set Qualitative Comparative Analysis"],"prefix":"10.1002","volume":"30","author":[{"given":"Patricia L.","family":"Haynes","sequence":"first","affiliation":[{"name":"Health Promotion Sciences University of Arizona  Tucson Arizona USA"},{"name":"Mental Health Care Line Southern Arizona VA Health Care System  Tucson Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Emert","sequence":"additional","affiliation":[{"name":"Biomedical Research Foundation of Southern Arizona  Tucson Arizona USA"},{"name":"Department of Psychology University of Alabama  Tuscaloosa Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Epstein","sequence":"additional","affiliation":[{"name":"Nursing Services Phoenix VA Health Care System  Phoenix Arizona USA"},{"name":"School of Nutrition and Health Promotion Arizona State University  Phoenix Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Perkins","sequence":"additional","affiliation":[{"name":"Mental Health Care Line Southern Arizona VA Health Care System  Tucson Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sairam","family":"Parthasarathy","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Arizona  Tucson Arizona USA"},{"name":"Research Service Southern Arizona VA Health Care System  Tucson Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Wilcox","sequence":"additional","affiliation":[{"name":"Mental Health Care Line Southern Arizona VA Health Care System  Tucson Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,21]]},"reference":[{"key":"e_1_2_5_2_1","volume-title":"International classification of sleep disorders: Diagnostic and coding manual","author":"American Academy of Sleep Medicine","year":"2005"},{"key":"e_1_2_5_3_1","first-page":"CD003388","article-title":"Psychological therapies for chronic post\u2010traumatic stress disorder (PTSD) in adults","volume":"12","author":"Bisson J. 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