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We explored the presence of trauma exposure in a sample of Spanish participants with FM and examined the associations between (a) the number and type of traumatic experiences and posttraumatic stress disorder (PTSD) symptoms and (b) the severity of clinical manifestations in FM, testing for possible mediation models. Participants were 173 FM patients and 53 healthy controls aged 24 to 66 years. Traumatic event type (physical trauma, physical and sexual abuse, psychological trauma), PTSD symptoms, pain intensity, sleep disturbance, anxiety, depression, coping style, and daily functioning were evaluated via self\u2010report. Fibromyalgia patients reported a higher percentage of trauma exposure than controls, more traumatic experiences (mainly emotional and physical trauma), and more PTSD symptoms, Hedges\u2019 <jats:italic>g<\/jats:italic>s\/Cohen's <jats:italic>d<\/jats:italic>s <jats:italic>=<\/jats:italic> 0.42\u20130.76. Most FM patients reported having experienced their most distressing traumatic experience and PTSD symptoms before FM diagnosis. PTSD symptom severity was associated with more pain, sleep disturbances, anxiety, depression, coping style, and functional impairment, <jats:italic>r<\/jats:italic>s = .23\u2013.33, <jats:italic>p<\/jats:italic>s = .025\u2013.008. A multiple mediation analysis showed a significant indirect effect of anxiety in the association between PTSD symptoms and daily functioning. In a subset of FM patients, PTSD symptoms were associated with major clinical symptoms. The results suggest future research should explore the effectiveness of trauma\u2010focused therapy compared to standard cognitive behavioral therapy for these patients.<\/jats:p>","DOI":"10.1002\/jts.22550","type":"journal-article","created":{"date-parts":[[2020,6,22]],"date-time":"2020-06-22T09:14:24Z","timestamp":1592817264000},"page":"1082-1092","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Clinical Manifestations of Trauma Exposure in Fibromyalgia: The Role of Anxiety in the Association Between Posttraumatic Stress Symptoms and Fibromyalgia Status"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0014-6355","authenticated-orcid":false,"given":"Elena","family":"Mir\u00f3","sequence":"first","affiliation":[{"name":"University of Granada Department of Personality, Assessment, and Psychological Treatment  Granada Spain"},{"name":"The Mind, Brain and Behavior Research Center  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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