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This prospective study aimed to investigate whether general psychopathology and posttraumatic stress disorder (PTSD) symptom severity increased during the pandemic as compared to prepandemic baseline data collected approximately 1 year earlier. Furthermore, we investigated whether an increase in symptomatology was linked to CTEs and mediated by a lack of perceived social support and fear of COVID\u201019. An online survey was administered to 85 individuals, including both participants with PTSD, major depression, or somatic symptom disorder (\n                    <jats:italic>n<\/jats:italic>\n                    = 63) and healthy volunteers (\n                    <jats:italic>n<\/jats:italic>\n                    = 22), during a period of the most severe social restrictions in Germany. The survey included the Childhood Trauma Questionnaire, Brief Symptom Inventory, PTSD Checklist for\n                    <jats:italic>DSM\u20105<\/jats:italic>\n                    , ENRICHD Social Support Inventory, and Fear of COVID\u201019 Scale. In the whole sample, we found significant increases in general psychopathology and PTSD symptom severity, \u03c9\n                    <jats:sup>2<\/jats:sup>\n                    = .07\u2013.08, during as compared to before the COVID\u201019 pandemic, with CTEs predicting increased PTSD symptom severity, \u03b2 = .245,\n                    <jats:italic>p<\/jats:italic>\n                    = .042. This effect was mediated by a lack of perceived social support, indirect effect = .101, 95% CI [.013, .209], but not fear of COVID\u201019, indirect effect = .060, 95% CI [\u2212.035, .167]. These findings emphasize the importance of interventions that promote social inclusion to mitigate the potentially detrimental effects of public health actions implemented against the COVID\u201019 pandemic in individuals with CTEs.\n                  <\/jats:p>","DOI":"10.1002\/jts.22660","type":"journal-article","created":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T23:16:43Z","timestamp":1613258203000},"page":"477-486","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["A Prospective Study of Mental Health During the COVID\u201019 Pandemic in Childhood Trauma\u2013Exposed Individuals: Social Support Matters"],"prefix":"10.1002","volume":"34","author":[{"given":"Katja I.","family":"Seitz","sequence":"first","affiliation":[{"name":"Department of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty Heidelberg University  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Bertsch","sequence":"additional","affiliation":[{"name":"Department of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty Heidelberg University  Heidelberg Germany"},{"name":"Department of Psychology Ludwig\u2010Maximilians\u2010University Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine C.","family":"Herpertz","sequence":"additional","affiliation":[{"name":"Department of General Psychiatry, Center for Psychosocial Medicine, Medical Faculty Heidelberg University  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11469-020-00270-8"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0161645"},{"key":"e_1_2_7_4_1","unstructured":"Beesdo\u2010Baum K. 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