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This study examined how childhood adversity affected physical and psychological symptoms associated with breast cancer treatment and survivorship at three points within the cancer trajectory. Breast cancer survivors (\n                    <jats:italic>N<\/jats:italic>\n                    = 209) were recruited following diagnosis and completed three visits at pretreatment, 6 months posttreatment, and 18 months posttreatment. All survivors completed the Childhood Trauma Questionnaire to assess abuse and neglect exposure prior to 18 years of age. At each visit, participants completed self\u2010report measures of depressive symptoms, anxiety symptoms, pain, fatigue, and sleep quality. When controlling for disease\u2010related variables, sexual abuse significantly interacted with study visit to predict pain,\n                    <jats:italic>p<\/jats:italic>\n                    =\u00a0.002. No other significant interactions emerged. Analyses of main effects revealed that breast cancer survivors who experienced higher rates of each abuse or neglect type experienced poorer sleep quality,\n                    <jats:italic>B<\/jats:italic>\n                    s = 0.20\u20130.39,\n                    <jats:italic>p<\/jats:italic>\n                    &lt;\u00a0.001\u2013\n                    <jats:italic>p<\/jats:italic>\n                    =\u00a0.002; higher fatigue,\n                    <jats:italic>B<\/jats:italic>\n                    s = 0.81\u20131.4,\n                    <jats:italic>p<\/jats:italic>\n                    s &lt;\u00a0.001\u2013\n                    <jats:italic>p<\/jats:italic>\n                    =\u00a0.020; more depressive symptoms,\n                    <jats:italic>B<\/jats:italic>\n                    s = 0.55\u20130.56,\n                    <jats:italic>p<\/jats:italic>\n                    s \u00a0.001; and higher anxiety symptoms,\n                    <jats:italic>B<\/jats:italic>\n                    s = 0.35\u20130.54,\n                    <jats:italic>p<\/jats:italic>\n                    &lt;\u00a0.001\u2013\n                    <jats:italic>p =<\/jats:italic>\n                    \u00a0.002. Only physical neglect was significantly associated with pain,\n                    <jats:italic>B<\/jats:italic>\n                    = 0.12,\n                    <jats:italic>p<\/jats:italic>\n                    =\u00a0.041. Results suggest that breast cancer survivors who experienced abuse and neglect earlier in life are at increased risk of adverse physical and psychological symptoms throughout survivorship. Providers should consider screening for early life trauma to understand unique risks associated with navigating breast cancer treatment and survivorship.\n                  <\/jats:p>","DOI":"10.1002\/jts.70057","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:50:35Z","timestamp":1774536635000},"page":"453-463","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Early life abuse and neglect in breast cancer survivors: Associations with physical and psychological health throughout diagnosis and survivorship"],"prefix":"10.1002","volume":"39","author":[{"given":"Sonal K.","family":"Johal","sequence":"first","affiliation":[{"name":"School of Psychology University of Southern Mississippi  Hattiesburg Mississippi USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Rosie","family":"Shrout","sequence":"additional","affiliation":[{"name":"Department of Psychology University of British Columbia  Vancouver, Canada USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annelise A.","family":"Madison","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie J.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Alabama Birmingham  Birmingham Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen P.","family":"Povoski","sequence":"additional","affiliation":[{"name":"Comprehensive Cancer Center The Ohio State University College of Medicine  Columbus Ohio USA"},{"name":"Department of Surgical Oncology The Ohio State University College of Medicine  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"William E.","family":"Carson","sequence":"additional","affiliation":[{"name":"Comprehensive Cancer Center The Ohio State University College of Medicine  Columbus Ohio USA"},{"name":"Department of Surgical Oncology The Ohio State University College of Medicine  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice K.","family":"Kiecolt\u2010Glaser","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Health The Ohio State University College of Medicine  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3941-4270","authenticated-orcid":false,"given":"Megan E.","family":"Renna","sequence":"additional","affiliation":[{"name":"Department of Psychology The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. 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