{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T08:57:14Z","timestamp":1780995434246,"version":"3.54.1"},"reference-count":31,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T00:00:00Z","timestamp":1495843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of the study was to evaluate the correlation between endometrioma\u2010associated pain and lesion vascularization as measured with 3\u2010dimensional power Doppler transvaginal sonography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Endometriomas were examined, and 4 indices were obtained: mean grayness, flow index, vascularization index, and vascularization\u2010flow index. Dysmenorrhea, chronic pelvic pain, and dyspareunia were analyzed in terms of severity, presence\/absence, and duration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010nine women were selected. The univariable association of painful symptoms in terms of presence\/absence and duration was low with the exception of mean grayness with the presence of chronic pelvic pain (\u03b2\u2009=\u2009\u20130.106;<jats:italic>P<\/jats:italic>\u2009=\u2009.047; 95% confidence interval, 0.810 to 0.998). The<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>value increased to 0.226 for dysmenorrhea (\u03b2\u2009=\u2009\u20130.475;<jats:italic>P<\/jats:italic>\u2009=\u2009.029) when analyzing the association between the vascularization index and the severity of painful symptoms. The visual analog scale scores for chronic pelvic pain and dyspareunia were higher (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20090.300; \u03b2\u2009=\u2009\u20130.547 and \u20130.548, respectively;<jats:italic>P<\/jats:italic>\u2009=\u2009.028 and .053).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We observed an inverse association between the severity of pain and endometrioma vascularization. Further larger studies are required to confirm our findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.14258","type":"journal-article","created":{"date-parts":[[2017,5,27]],"date-time":"2017-05-27T06:36:44Z","timestamp":1495867004000},"page":"2271-2278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Three\u2010Dimensional Power Doppler Vascularization in Women With Ovarian Endometriomas and Relationship With Associated Painful Symptoms"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4869-7367","authenticated-orcid":false,"given":"Francesca","family":"Rizzello","sequence":"first","affiliation":[{"name":"Department of Clinical and Experimental Biomedical Sciences University of Florence, Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Capezzuoli","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Biomedical Sciences University of Florence, Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ippolita","family":"D'Amato Scherbatoff","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Biomedical Sciences University of Florence, Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Cozzolino","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Biomedical Sciences University of Florence, Florence Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loredana","family":"Gandini","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Biomedical Sciences University of Florence, Florence Italy"},{"name":"Department of Experimental Medicine, Section of Medical Physiopathology University of Rome La Sapienza Rome 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