{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:07:21Z","timestamp":1792098441089,"version":"4.4.0"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,7,31]],"date-time":"2017-07-31T00:00:00Z","timestamp":1501459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"New York University Clinical and Translational Science Award from the National Center for Advancing Translational Sciences, National Institutes of Health","award":["Grant UL1 TR001445"],"award-info":[{"award-number":["Grant UL1 TR001445"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Objective measures of clinical improvement in patients with acute heart failure (AHF) are lacking. The aim of this study was to determine whether repeated lung sonography could semiquantitatively capture changes in pulmonary edema (B\u2010lines) in patients with hypertensive AHF early in the course of treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a feasibility study in a cohort of adults with acute onset of dyspnea, severe hypertension in the field or at triage (systolic blood pressure\u2009\u2265\u2009180\u2009mm Hg), and a presumptive diagnosis of AHF. Patients underwent repeated dyspnea and lung sonographic assessments using a 10\u2010cm visual analog scale (VAS) and an 8\u2010zone scanning protocol. Lung sonographic assessments were performed at the time of triage, initial VAS improvement, and disposition from the emergency department. Sonographic pulmonary edema was independently scored offline in a randomized and blinded fashion by using a scoring method that accounted for both the sum of discrete B\u2010lines and degree of B\u2010line fusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sonographic pulmonary edema scores decreased significantly from initial to final sonographic assessments (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). The median percentage decrease among the 20 included patient encounters was 81% (interquartile range, 55%\u201391%). Although sonographic pulmonary edema scores correlated with VAS scores (\u03c1\u2009=\u20090.64; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), the magnitude of the change in these scores did not correlate with each other (\u03c1\u2009=\u2009\u20130.04; <jats:italic>P<\/jats:italic>\u2009=\u2009.89).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Changes in sonographic pulmonary edema can be semiquantitatively measured by serial 8\u2010zone lung sonography using a scoring method that accounts for B\u2010line fusion. Sonographic pulmonary edema improves in patients with hypertensive AHF during the initial hours of treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.14336","type":"journal-article","created":{"date-parts":[[2017,7,31]],"date-time":"2017-07-31T11:12:47Z","timestamp":1501499567000},"page":"337-345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Serial Sonographic Assessment of Pulmonary Edema in Patients With Hypertensive Acute Heart Failure"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9042-3183","authenticated-orcid":false,"given":"Jennifer L.","family":"Martindale","sequence":"first","affiliation":[{"name":"State University of New York Downstate Medical Center Brooklyn New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Secko","sequence":"additional","affiliation":[{"name":"Stony Brook University Hospital Stony Brook New 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