{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T20:03:55Z","timestamp":1770753835971,"version":"3.50.0"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T00:00:00Z","timestamp":1508112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Science and Technology Committee of Shanghai","award":["20144Y0096"],"award-info":[{"award-number":["20144Y0096"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of this study was to investigate the stiffness of the cervix after the loop electrosurgical excision procedure (LEEP) by transvaginal elastography and its potential ability to predict future pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study included patients of reproductive age who underwent LEEP for cervical high\u2010grade squamous intraepithelial lesions on the basis of colposcopic findings and who desired fertility. The characteristics on conventional transvaginal ultrasonography and elastography before and 6 months after LEEP were reviewed and analyzed. Each case had a 12\u2010month follow\u2010up, and the information on pregnancy and a cervical cytologic examination was recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010three patients who completed the 12\u2010month follow\u2010up were included in the analysis. Thirty\u2010two cases (group 1) were pregnant during the follow\u2010up, and the other 21 (group 2) had pregnancy failure. The cervical lengths of group 1 and 2 as measured by traditional transvaginal ultrasonography were similar before and 6 months after LEEP. The resistive index of group 1 was significantly higher 6 months after LEEP than before LEEP (mean\u2009\u00b1\u2009SD, 0.88\u2009\u00b1\u20090.36 versus 0.42\u2009\u00b1\u20090.22; <jats:italic>P<\/jats:italic>\u2009=\u2009.007). The mean elasticity score for the cervix was statistically significantly lower after LEEP (2.21\u2009\u00b1\u20090.53) than before (3.46\u2009\u00b1\u20090.78; <jats:italic>P<\/jats:italic>\u2009=\u2009.001) in group 1. However, in group 2, the mean elasticity scores were similar after LEEP (3.19\u2009\u00b1\u20090.58) and before (3.25\u2009\u00b1\u20090.66; <jats:italic>P<\/jats:italic>\u2009=\u2009.75).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our results suggest that elastography was a useful technique for evaluating the stiffness of the cervix after LEEP. Elastography could provide a potential means to predict future pregnancy after LEEP.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.14457","type":"journal-article","created":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T20:02:25Z","timestamp":1508184145000},"page":"1109-1114","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of the Cervix After Cervical Conization by Transvaginal Elastography"],"prefix":"10.1002","volume":"37","author":[{"given":"Meng","family":"Xie","sequence":"first","affiliation":[{"name":"Departments of Ultrasound Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuyin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Departments of Gynecology, Obstetrics and Gynecology Hospital Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Yu","sequence":"additional","affiliation":[{"name":"Departments of Gynecology, Obstetrics and Gynecology Hospital Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0467-5916","authenticated-orcid":false,"given":"Wenping","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5359-8841","authenticated-orcid":false,"given":"Keqin","family":"Hua","sequence":"additional","affiliation":[{"name":"Departments of Gynecology, Obstetrics and Gynecology Hospital Fudan University Shanghai 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