{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T11:21:19Z","timestamp":1778498479463,"version":"3.51.4"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of this study was to evaluate the imaging features of clear cell hidradenoma on ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The radiologic and pathologic databases at 2 medical institutions were searched retrospectively from 2004 to 2016 to identify patients with a diagnosis of clear cell hidradenoma. Ultrasonographic, CT, and MRI features were described, and pathologic specimens were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 5 female and 4 male patients. The mean patient age was 48.9 years (range, 28\u201370 years). Five patients underwent only US; 2 patients underwent only CT; 1 patient underwent both US and CT; and 1 patient underwent US and MRI. Most of the tumors were located primarily in the subcutaneous fat layer. The mean tumor size was 18.4\u2009mm. On US, 6 masses had a heterogeneous echo texture, including an anechoic portion with protruding echogenic portions. Two masses had multiple septa in the anechoic portion. On color Doppler US, blood flow was both central and peripheral in 5 patients. All 3 cases seen on CT presented as a low\u2010attenuation mass with an enhanced solid internal nodule. On MRI, the mass showed heterogeneous signal intensity on T2\u2010weighted images and enhancement of the peripheral wall and internal solid component on contrast\u2010enhanced T1\u2010weighted images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Clear cell hidradenoma is usually located in the subcutaneous fat layer, has a well\u2010defined margin, appears as a cystic mass with an internal solid nodule, and occasionally has multiple septa on US, CT, and MRI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.14552","type":"journal-article","created":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T06:23:25Z","timestamp":1517466205000},"page":"1993-2001","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Clear Cell Hidradenoma: Characteristic Imaging Features on Ultrasonography, Computed Tomography, and Magnetic Resonance Imaging"],"prefix":"10.1002","volume":"37","author":[{"given":"Joo Yeon","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology University of Ulsan College of Medicine, Asan Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1662-7206","authenticated-orcid":false,"given":"Byeong Seong","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Ulsan College of Medicine, Ulsan University Hospital Ulsan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Seok","family":"Shim","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Ulsan College of Medicine, Ulsan University Hospital Ulsan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In Hye","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Pathology  University of Ulsan College of Medicine, Asan Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Ulsan College of Medicine, Ulsan University Hospital Ulsan Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology University of Ulsan College of Medicine, Asan Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Won","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology University of Ulsan College of Medicine, Asan Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Hee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology University of Ulsan College of Medicine, Asan Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Jin","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiology University of Ulsan College of Medicine, Asan Medical Center Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1001\/archderm.1967.01610010024003","article-title":"Clear cell hidradenoma: histologic, histochemical and electron microscopic study","volume":"96","author":"Hashimoto K","year":"1967","journal-title":"Arch 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