{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T18:10:53Z","timestamp":1781115053025,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,5,6]],"date-time":"2018-05-06T00:00:00Z","timestamp":1525564800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Association of University Radiologists and General Electric through the AURGERRAF fellowship program"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study evaluated the diagnostic performance of transvaginal ultrasound (TVUS) shear wave elastography (SWE) for evaluating uterine adenomyosis and leiomyomas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Institutional Review Board approval was obtained for prospective enrollment of 34 premenopausal women with pelvic pain and\/or bleeding between January 2015 and June 2016. TVUS SWE was performed with regions of interest in multiple uterine segments and shear wave velocities(SWVs) were recorded. Reference pelvic magnetic resonance examinations were performed and reviewed without access to the ultrasound results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Continuous variables were analyzed using means, <jats:italic>t<\/jats:italic> tests, and analysis of variance. Magnetic resonance imaging revealed adenomyosis in 6 women (12 uterine segments) and leiomyomas in 12 women (28 segments). On a per\u2010patient basis, mean SWV in 16 women with no adenomyosis or leiomyoma was 4.3\u2009\u00b1\u20091.7\u2009m\/s, compared with 5.7\u2009\u00b1\u20092.3\u2009m\/s in 18 women with a magnetic resonance diagnosis of myometrial pathology (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.0002; 95% confidence interval, \u22122.2, \u22120.6). On a per\u2010segment basis, SWV in normal myometrium was 4.8\u2009\u00b1\u20091.9\u2009m\/s, compared with 4.9\u2009\u00b1\u20092.5\u2009m\/s in adenomyosis and 5.6\u2009\u00b1\u20092.5\u2009m\/s in leiomyoma (<jats:italic>P<\/jats:italic>\u2009=\u2009.34 by one\u2010way analysis of variance). In pairwise comparison, SWV for adenomyosis and leiomyoma did not differ significantly (<jats:italic>P<\/jats:italic>\u2009=\u2009.40).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>TVUS SWE did not distinguish adenomyosis from leiomyoma. However, our pilot study demonstrated that myometrial SWVs were higher in uteri with adenomyosis and leiomyomas than in uteri with myometrium with no abnormalities suggesting a potential role for SWE in treatment response assessment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.14676","type":"journal-article","created":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T06:51:40Z","timestamp":1525675900000},"page":"149-155","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Transvaginal Ultrasound Shear Wave Elastography for the Evaluation of Benign Uterine Pathologies: A Prospective Pilot Study"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7153-4881","authenticated-orcid":false,"given":"Man","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Radiology University of Michigan Ann Arbor Michigan USA"},{"name":"Department of Radiology University of Washington 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