{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:48:11Z","timestamp":1786978091363,"version":"build-2736575974"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T00:00:00Z","timestamp":1542067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of the study was to scrutinize the value of qualitative elastography in the diagnosis of salivary gland masses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sixty patients were enrolled in this prospective study. Patients aged between 1 and 91 years (mean age, 48.8\u2009\u00b1\u200920.48) with a salivary gland mass were studied with real\u2010time elastography. All patients were examined by 1 examiner, blinded to all relevant data. On elastography, masses were scored into 4 types according to their stiffness compared to normal tissue. Scores of 3 and 4 were accepted as signs of malignancy. Sensitivity, specificity, and positive and negative predictive value were calculated for elastography in verifying malignancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty\u2010two percent of the masses were located in the parotid, and the rest in submandibular gland. The diameter of the lesions varied between 12 and 60\u2009mm (mean, 24.36\u2009\u00b1\u200911.98\u2009mm). Forty\u2010four masses were benign (73%), and among them the majority were inflammatory lesions (31 of 60; 51.7%). There were 16 malignant lesions (27%). On elastography, not only all malignant lesions but 15 benign lesions were scored as 3 to 4. All masses scored as 1 to 2 were benign. Sensitivity was 100%; specificity, 66%; positive predictive value, 52%; and negative predictive value, 100%. When only Score 4 lesions were accepted as malignant, these values became 75%, 77%, 55%, and 90%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Elastography alone cannot be used to discriminate malignant from benign in the evaluation of salivary gland lesions. However, with its high negative predictive value, it may be used as an adjunct tool to increase the diagnostic value of ultrasonography.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jum.14851","type":"journal-article","created":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T23:25:08Z","timestamp":1542151508000},"page":"1677-1683","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Role of Real\u2010Time Elastography in the Differential Diagnosis of Salivary Gland Tumors"],"prefix":"10.1002","volume":"38","author":[{"given":"Can Zafer","family":"Karaman","sequence":"first","affiliation":[{"name":"Department of Radiology  Ayd\u0131n Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sema","family":"Ba\u015fak","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Adnan Menderes University Hospital  Ayd\u0131n Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4452-6632","authenticated-orcid":false,"given":"Yasemin Durum","family":"Polat","sequence":"additional","affiliation":[{"name":"Department of Radiology  Ayd\u0131n Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alparslan","family":"\u00dcnsal","sequence":"additional","affiliation":[{"name":"Department of Radiology  Ayd\u0131n Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00fcsun","family":"Ta\u015fk\u0131n","sequence":"additional","affiliation":[{"name":"Department of Radiology  Ayd\u0131n Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"Kaya","sequence":"additional","affiliation":[{"name":"Surreyyapasa Chest Diseases and Thoracic Surgery Training Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ceren","family":"G\u00fcnel","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Adnan Menderes University Hospital  Ayd\u0131n Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1102\/1470-7330.2013.0026"},{"key":"e_1_2_6_3_1","first-page":"175","article-title":"Ultrasonographic and sonoelastographic features of pleomorphic adenomas of the salivary glands","volume":"12","author":"Dumitriu D","year":"2010","journal-title":"Med Ultrason"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.01.027"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-002-1586-9"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-010-1756-0"},{"key":"e_1_2_6_7_1","first-page":"175","article-title":"Ultrasonographic and sonoelastographic features of pleomorphic adenomas of the salivary glands","volume":"12","author":"Dumitriu D","year":"2010","journal-title":"Med Ultrason"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.6529"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2012.31.7.1083"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1258\/ar.2012.120405"},{"key":"e_1_2_6_11_1","unstructured":"DimitriuD.Ultrasound elastography features of major salivary gland tumours. In: Proceedings of the Radiological Society of North America 94th Scientific Assembly and Annual Meeting Chicago 2008."},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-012-2401-x"},{"key":"e_1_2_6_13_1","first-page":"397","article-title":"Shear wave elastography of focal salivary gland lesions: preliminary experience in a routine head and neck US clinic","volume":"22","author":"Bhatia KS","year":"2011","journal-title":"Eur Radiol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.15.08043"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-011-2344-7"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.11152\/mu-923"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-119412"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2013.07.008"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjum.14851","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.14851","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.14851","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.14851","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T08:12:24Z","timestamp":1694333544000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.14851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,13]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1002\/jum.14851"],"URL":"https:\/\/doi.org\/10.1002\/jum.14851","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,13]]},"assertion":[{"value":"2018-04-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-10-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}