{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T15:24:44Z","timestamp":1787585084243,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T00:00:00Z","timestamp":1545350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Kirikkale University Scientific Research Projects and Coordination Unit","award":["2018\/036"],"award-info":[{"award-number":["2018\/036"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the optic nerve's elastic properties using shear wave and strain elastography in patients with migraine compared to healthy individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The migraine group consisted of 30 patients (16 with visual auras and 14 without auras) who had previously had a diagnosis of migraine. These were age and sex matched with healthy participants to form the control group. The findings from shear wave and strain elastography in the groups were compared. The elastographic examination was performed with a 6\u201315\u2010MHz multifrequency linear array transducer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The evaluation involved 30 patients with migraine (3 male and 27 female), whose mean age\u2009\u00b1\u2009SD was 34.63\u2009\u00b1\u200910\u2009years, and 30 healthy participants (3 males, 27 females), whose mean age was 36.4\u2009\u00b1\u200910.5\u2009years. In strain elasticity patterns, a statistically insignificant hardening of the optic nerve in the patients with migraine was observed (<jats:italic>P<\/jats:italic>\u2009=\u2009.052). Analysis of the shear wave elastic modulus values (9.8\u2009\u00b1\u20093.34 and 12.3\u2009\u00b1\u20095.25\u2009kPa; <jats:italic>P<\/jats:italic>\u2009=\u2009.03) revealed that differences between the healthy participants and patients with migraine were statistically significant. The results for elasticity patterns and the shear modulus suggested that the differences between migraines with and without visual auras were insignificant (<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.05). A positive correlation was discovered between the duration of the disease and the shear modulus in the patients with migraine (<jats:italic>r<\/jats:italic>\u2009=\u20090.496; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Histopathologic changes in the optic nerve may be seen in patients with migraine due to possible fibrotic changes. Elastographic techniques can be useful diagnostic tools for investigating these changes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.14904","type":"journal-article","created":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T05:34:38Z","timestamp":1545456878000},"page":"1153-1161","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Evaluation of the Optic Nerve by Strain and Shear Wave Elastography in Patients With Migraine"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8976-6157","authenticated-orcid":false,"given":"Mehmet Hamdi","family":"\u015eahan","sequence":"first","affiliation":[{"name":"Department of Radiology Faculty of Medicine Kirikkale University  Kirikkale Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adil","family":"Do\u011fan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine Kahramanmaras Sutcu 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