{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T22:54:55Z","timestamp":1761519295507,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T00:00:00Z","timestamp":1582243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of this study was to investigate the contribution of strain index measurements and a 5\u2010point scoring method to diagnostic accuracy in differential diagnosis of benign and malignant solid breast masses and to compare the diagnostic performances of both methods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty female patients were included in this study. Before biopsy, all patients underwent ultrasound (US) and sonoelastographic examinations. The elastographic images of lesions were assessed according to the 5\u2010point scoring method, and then elasticity scores were determined. Strain values of the masses and subcutaneous adipose tissue were measured. The diagnostic efficacies of B\u2010mode US, sonoelastographic 5\u2010point scoring, and strain index methods were compared with histopathologic findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of the patients \u00b1 SD was 42\u2009\u00b1\u200913\u2009years (range, 14\u201381\u2009years). In histopathologic evaluations, 59 (74%) lesions were diagnosed as benign, and 21 (26%) were diagnosed as malignant. The mean strain index values were 10.45\u2009\u00b1\u20097.04 (range, 3.4\u201325.1) in malignant lesions and 2.88\u2009\u00b1\u20092.5 (range, 0.5\u201319.81) in benign lesions. The mean strain index for malignant lesions was significantly higher than that for benign lesions (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). The highest sensitivity was found for B\u2010mode US, and the highest specificity was found for the strain index. The diagnostic performance of the strain index was higher than that of the 5\u2010point scoring method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The addition of a sonoelastographic examination to B\u2010mode US prevents unnecessary biopsies. The strain index was found to be superior to the 5\u2010point scoring method to a limited extent.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15236","type":"journal-article","created":{"date-parts":[[2020,2,21]],"date-time":"2020-02-21T11:15:25Z","timestamp":1582283725000},"page":"1395-1403","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Contribution of Sonoelastography to Diagnosis in Distinguishing Benign and Malignant Breast Masses"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0804-0547","authenticated-orcid":false,"given":"Mehmet S\u0131dd\u0131k","family":"Y\u0131ld\u0131z","sequence":"first","affiliation":[{"name":"Batman Dunya Hospital  Batman Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cemil","family":"Goya","sequence":"additional","affiliation":[{"name":"Van Y\u00fcz\u00fcnc\u00fc Y\u0131l University Faculty of Medicine  Van Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0070-9998","authenticated-orcid":false,"given":"Mehmet Emin","family":"Adin","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,21]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"7","volume-title":"Breast Imaging","author":"Kopans DB","year":"1998"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.162.1.3024209"},{"key":"e_1_2_6_4_1","first-page":"199","article-title":"Contrast enhanced power Doppler and color Doppler ultrasound in breast masses: efficiency in diagnosis and contributions to differential diagnosis","volume":"9","author":"Alg\u00fcl A","year":"2003","journal-title":"Tani Girisim Radyol"},{"key":"e_1_2_6_5_1","first-page":"67","article-title":"The diagnostic importance of evaluation of solid breast masses by sonoelastography","volume":"29","author":"Yerli H","year":"2013","journal-title":"Ulus Cerrahi Derg"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2008.08.003"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2009.12.006"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2716"},{"volume-title":"Breast Imaging Reporting and Data System: Ultrasound","year":"2004","author":"American College of Radiology","key":"e_1_2_6_9_1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2391041676"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.196.1.7784555"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0221-0363(07)89872-6"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2008.01.004"},{"key":"e_1_2_6_14_1","unstructured":"UenoE UmemotoT BandoH TohnoE WakiK MatsumuraT.New quantitative method in breast elastography: fat\u2010lesion ratio (FLR). 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