{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:37:31Z","timestamp":1769603851960,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T00:00:00Z","timestamp":1582156800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of this study was to compare the ultrasound\u2010measured inferior vena cava distensibility index (IVCdi), inferior vena cava distensibility variability (IVCdv), and inferior vena cava\u2013to\u2013aorta ratio (IVC\/Ao) to other common methods to assess fluid status in mechanically ventilated pediatric critically ill patients. These methods include central venous pressure (CVP), percent fluid overload by weight (%FOw), and percent fluid overload by volume (%FOv).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective observational study of a convenience sample of 50 mechanically ventilated pediatric patients. Ultrasound measurements of the inferior vena cava and aorta were obtained, and the IVCdi, IVCdv, and IVC\/Ao were calculated and compared to CVP, %FOw, and %FOv.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median %FOw was 5%, and the median %FOv was 10%. The mean CVP \u00b1 SD was 8.6 \u00b1\u20094\u2009mm Hg. The CVP had no significant correlation with %FOw or %FOv. There was no significant correlation of the IVCdi with CVP (<jats:italic>r<\/jats:italic> = \u20130.145; <jats:italic>P<\/jats:italic> = .325) or %FOv (<jats:italic>r<\/jats:italic> =\u20090.119; <jats:italic>P<\/jats:italic> = .420); however, the IVCdi had a significant correlation with %FOw (<jats:italic>P<\/jats:italic> = .012). There was also no significant relationship of the IVCdv with CVP (<jats:italic>r<\/jats:italic> = \u20130.135; <jats:italic>P<\/jats:italic> = .36) or %FOv (<jats:italic>r<\/jats:italic> =\u20090.128; <jats:italic>P<\/jats:italic> = .385); however, there was a significant correlation between the IVCdv and %FOw (<jats:italic>P<\/jats:italic> = .012). There was no relationship between the IVC\/Ao and any other measures of fluid status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this cohort of mechanically ventilated pediatric intensive care unit patients, many commonly used markers of fluid status showed weak correlations with each other. The IVCdi and IVCdv significantly correlated with %FOw and may have potential as markers for fluid overload in this patient population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15247","type":"journal-article","created":{"date-parts":[[2020,2,20]],"date-time":"2020-02-20T15:21:31Z","timestamp":1582212091000},"page":"1573-1579","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Point\u2010of\u2010Care Ultrasound Assessment of the Inferior Vena Cava in Mechanically Ventilated Critically Ill Children"],"prefix":"10.1002","volume":"39","author":[{"given":"Sonali","family":"Basu","sequence":"first","affiliation":[{"name":"Divisions of Critical Care Medicine Children's National Health System  Washington DC USA"},{"name":"George Washington University School of Medicine and Health Sciences  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Sharron","sequence":"additional","affiliation":[{"name":"Divisions of Critical Care Medicine Children's National Health System  Washington DC USA"},{"name":"George Washington University School of Medicine and Health Sciences  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Herrera","sequence":"additional","affiliation":[{"name":"Divisions of Critical Care Medicine Children's National Health System  Washington DC USA"},{"name":"George Washington University School of Medicine and Health Sciences  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa","family":"Mize","sequence":"additional","affiliation":[{"name":"Divisions of Critical Care Medicine Children's National Health System  Washington DC USA"},{"name":"George Washington University School of Medicine and Health Sciences  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9318-8927","authenticated-orcid":false,"given":"Joanna","family":"Cohen","sequence":"additional","affiliation":[{"name":"Emergency Medicine Children's National Health System  Washington DC USA"},{"name":"George Washington University School of Medicine and Health Sciences  Washington DC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2018.00306"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-015-2592-7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31825bc54d"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31822882a3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"e0160093","DOI":"10.1371\/journal.pone.0160093","article-title":"Association of fluid accumulation with clinical outcomes in critically ill children with severe sepsis","volume":"11","author":"Chen J","year":"2016","journal-title":"PLoS One"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2017.4540"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.10.048"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31819323c6"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2010.11.001"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31828a25fd"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-011-2231-3"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(90)90711-9"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.02.062"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2009.04.021"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2259-8"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2233-5"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.12310"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000003459"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14752"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0146859"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e31828512a5"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.107.6.1309"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2012.02591.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1067\/mje.2002.120701"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0873-2159(15)30457-8"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2004.01.004"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14574"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjum.15247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.15247","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T16:36:44Z","timestamp":1693931804000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.15247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,20]]},"references-count":27,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1002\/jum.15247"],"URL":"https:\/\/doi.org\/10.1002\/jum.15247","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,20]]},"assertion":[{"value":"2019-09-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}