{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:08:00Z","timestamp":1787836080501,"version":"build-2784847793"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T00:00:00Z","timestamp":1598659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Compare the accuracy of the Hadlock, the NICHD, and the Fetal Medicine Foundation (FMF) charts to detect large\u2010for\u2010gestational\u2010age (LGA) and adverse neonatal outcomes (as a secondary outcome).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a secondary analysis from a prospective study that included singleton non\u2010anomalous gestations with growth ultrasound at 26\u201336\u2009weeks. LGA was suspected with estimated fetal weight\u2009&gt;\u200990<jats:sup>th<\/jats:sup> percentile by the NICHD, FMF, and Hadlock charts. LGA was diagnosed with birth weight\u2009&gt;\u200990<jats:sup>th<\/jats:sup> percentile. We tested the performance of these charts to detect LGA and adverse neonatal outcomes (neonatal intensive care unit admission, Ph\u2009&lt;\u20097.1, Apgar &lt;7 at 5\u2009minutes, seizures, and neonatal death) by calculating the area under the curve, sensitivity, specificity, positive predictive value, and negative predictive value.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 1054 pregnancies, 123 neonates (12%) developed LGA. LGA was suspected in 58 (5.5%) by Hadlock, 229 (21.7%) by NICHD standard, and 231 (22%) by FMF chart. The NICHD standard (AUC: .79; 95% CI: .75\u2013.83 vs. AUC .64; 95%CI: .6\u2013.68; p = &lt; .001) and FMF chart (AUC: .81 95% CI: .77\u2013.85 vs. AUC .64; 95%CI: .6\u2013.68; p = &lt; .001) were more accurate than Hadlock. The FMF and NICHD had higher sensitivity (77.2 vs. 72.4 vs. 30.1%) but Hadlock had higher specificity for LGA (97.5 vs. 88.5 vs. 85.4%). All standards were poor predictors for adverse neonatal outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The NICHD and the FMF standards may increase the detection rate of LGA in comparison to the Hadlock chart. However, this may increase obstetrical interventions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15470","type":"journal-article","created":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T09:24:30Z","timestamp":1598693070000},"page":"963-970","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Prediction of Large\u2010for\u2010Gestational\u2010Age Neonates by Different Growth Standards"],"prefix":"10.1002","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8464-9744","authenticated-orcid":false,"given":"Jose R.","family":"Duncan","sequence":"first","affiliation":[{"name":"University of South Florida, Department of Obstetrics and Gynecology  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Odibo","sequence":"additional","affiliation":[{"name":"University of South Florida, Department of Obstetrics and Gynecology  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Hoover","sequence":"additional","affiliation":[{"name":"University of South Florida, Department of Obstetrics and Gynecology  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony O.","family":"Odibo","sequence":"additional","affiliation":[{"name":"University of South Florida, Department of Obstetrics and Gynecology  Tampa Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001767"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.02.035"},{"key":"e_1_2_6_4_1","first-page":"754","article-title":"Birth trauma. 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