{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:19:26Z","timestamp":1759331966825,"version":"3.40.5"},"reference-count":18,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T00:00:00Z","timestamp":1607040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the relationship between choroidal nevus and melanoma thickness measured with or without the sclera included by B\u2010scan ultrasound and to present a simple conversion formula.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records were retrospectively reviewed for choroidal nevus or melanoma evaluated at the Mayo Clinic in Rochester, Minnesota, with B\u2010scan ultrasound between February 4, 2004, and April 23, 2020. Charts were retrospectively reviewed for high\u2010quality B\u2010scan images in which the ultrasound transducer was perpendicular to the lesion, measuring the tumor thickness without the sclera included. Measurements were repeated with the sclera included for each patient. Univariate and multiple linear regression analyses were performed to identify factors correlated with scleral thickness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 201 tumors included in the study, with a mean patient age\u2009\u00b1\u2009SD of 61\u2009\u00b1\u200914\u2009years, largest tumor basal diameter of 11.8\u2009\u00b1\u20094.8\u2009mm, tumor thickness without the sclera included of 3.72\u2009\u00b1\u20092.7\u2009mm, and thickness with the sclera included of 4.54\u2009\u00b1\u2009SD 2.8\u2009mm. On the univariate analysis, factors associated with perceived scleral thickness by B\u2010scan ultrasound included age (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), tumor thickness (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), and basal diameter (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.06). On the multivariate analysis, factors associated with perceived scleral thickness included age and tumor thickness (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) for all tumors and for the subset of 141 tumors with a thickness of 2\u2009mm or greater (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). For tumors of 2\u2009mm or greater in thickness, perceived scleral thickness by ultrasound can be estimated by the formula 0.00495(patient age)\u2009+\u20090.02451(tumor thickness without the sclera)\u2009+\u20090.42549.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We present a simple formula for converting between B\u2010scan ultrasound measurements of choroidal nevus and melanoma measuring 2\u2009mm or greater in thickness with and without the sclera included.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15575","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T11:53:07Z","timestamp":1607082787000},"page":"1911-1917","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Conversion Factor for <scp>B\u2010Scan<\/scp> Ultrasound Measurement of Intraocular Tumors With and Without the Sclera"],"prefix":"10.1002","volume":"40","author":[{"given":"Laurel B.","family":"Tanke","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Leske","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9710-4284","authenticated-orcid":false,"given":"Lauren A.","family":"Dalvin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Mayo Clinic  Rochester Minnesota 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