{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:15:20Z","timestamp":1788542120839,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:00:00Z","timestamp":1614902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The safest mode of delivery in low\u2010lying placenta is debatable. Little is known about outcomes in low\u2010lying placenta resolved during the late third trimester.<\/jats:p><jats:p>We compare outcomes of women with persistent versus resolved low\u2010lying placenta.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis on a prospective cohort of women with low\u2010lying placenta confirmed at 28\u201330\u2009weeks sonography (01\/2009 to 03\/2018). Women were followed up serially every 2 to 3\u2009weeks until delivery to assess the placental edge\u2010to\u2010internal os distance (IOD), and included if scan was performed within 28\u2009days before delivery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 86 women: in 21 the low\u2010lying placenta resolved, whereas in 65 persisted (<jats:italic>n<\/jats:italic>\u00a0=\u00a015 IOD 1\u201310\u2009mm, <jats:italic>n<\/jats:italic>\u00a0=\u00a050 IOD 11\u201320\u2009mm). Antepartum bleeding associated with higher rates of urgent cesarean delivery in 1\u201310\u2009mm (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.041) but not in 11\u201320\u2009mm (<jats:italic>P<\/jats:italic>\u00a0=\u00a01.000) and\u2009&gt;20\u2009mm (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.333). Among women with IOD &gt;10\u2009mm allowed to labor, vaginal delivery occurred in 76.7% (11\u201320\u2009mm) and 94.1% (&gt;20\u2009mm) (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.155), with no difference according to parity (70% and 80% in multiparas, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.696; 60% and 72.7% in nulliparas, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.698). Severe PPH (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.922) and hemoglobin drop (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.109) were similar among groups. Women with IOD 11\u201320\u2009mm and\u2009&gt;20\u2009mm and vaginal delivery bled less than women with similarly located placenta and cesarean delivery (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.009 and <jats:italic>P<\/jats:italic>\u00a0=\u00a0.048).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Women with IOD &gt;10\u2009mm have high chances of deliver vaginally with no further increase of their hemorrhagic risk. Success of vaginal delivery is independent of parity and antepartum bleeding. Labor should be managed in an adequate hospital setting.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15687","type":"journal-article","created":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T07:12:32Z","timestamp":1615014752000},"page":"123-133","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Pregnancy and Delivery Outcomes in Women With Persistent Versus Resolved Low\u2010Lying Placenta in the Late Third Trimester"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6898-7217","authenticated-orcid":false,"given":"Sara","family":"Ornaghi","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, MBBM Foundation at San Gerardo Hospital University of Milan\u2010Bicocca School of Medicine and Surgery  Monza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isadora","family":"Vaglio Tessitore","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, MBBM Foundation at San Gerardo Hospital University of Milan\u2010Bicocca School of Medicine and Surgery  Monza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrizia","family":"Vergani","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, MBBM Foundation at San Gerardo Hospital University of Milan\u2010Bicocca School of Medicine and Surgery  Monza Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.06.010"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.02.028"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2013.06.017"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(88)80009-7"},{"key":"e_1_2_7_6_1","unstructured":"LockwoodC Russo\u2010StieglitzK.Placenta previa: Management. Retrieved December 28 2018 fromhttps:\/\/wwwuptodatecom\/contents\/placenta-previa-management;2018."},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000001005"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogc.2015.12.009"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.22023"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1570118"},{"key":"e_1_2_7_11_1","article-title":"Modus partus bij placenta praevia marginalis","author":"Derks J","year":"2015","journal-title":"Nederlands Vereniging voor Obstet Gynaecol"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.06.009"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6304"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogc.2019.07.019"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2011.01776.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1701-2163(15)30508-9"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1051023"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1181168"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.15306"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2008.089"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1997.09010022.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.05.059"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000002237"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000000233"},{"key":"e_1_2_7_25_1","unstructured":"reVITALize Obstetric Data Definitions.https:\/\/www.acog.org\/About-ACOG\/ACOG-Departments\/Patient-Safety-and-Quality-Improvement\/reVITALize-Obstetric-Data-Definitions?IsMobileSet=false(Accessed Feb 25 2019)."},{"key":"e_1_2_7_26_1","unstructured":"National Collaborating Centre for Ws Children's H. National Institute for Health and Care Excellence: Clinical Guidelines.Intrapartum Care: Care of Healthy Women and Their Babies During Childbirth. London: National Institute for Health and Care Excellence (UK) Copyright \u00a9 2014 National Collaborating Centre for Women's and Children's Health;2014."},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2003.02491.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1159\/000333309"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90465-4"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1701-2163(16)32401-x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1701-2163(15)30503-x"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.15622"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2011.125"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2003.10.039"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2015.10.015"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041114"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0170194"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0020-7292(03)00211-x"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.16022"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/jmf.10.6.414.419"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13829"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.01.017"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.08.034"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00450.x"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1996.15.6.441"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10396-017-0791-8"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181da213e"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15687","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.15687","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15687","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T07:47:50Z","timestamp":1693208870000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.15687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,5]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1002\/jum.15687"],"URL":"https:\/\/doi.org\/10.1002\/jum.15687","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,5]]},"assertion":[{"value":"2020-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}