{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T19:58:12Z","timestamp":1781294292534,"version":"3.54.1"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T00:00:00Z","timestamp":1618876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Direct ultrasound imaging findings alone have low sensitivity for diagnosing duodenal (65%) and gastric ulcers (40%). This retrospective study evaluated the efficiency of ultrasound in detecting gastric\/duodenal ulcers in pediatric patients through direct and indirect findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We evaluated 244 children who underwent ultrasound and subsequent endoscopy within 4\u2009weeks for direct and indirect imaging findings indicative of gastric\/duodenal ulcers. Positive direct imaging findings revealed gastric or duodenal wall thickness &gt;8 or 5\u2009mm, respectively, and indirect findings revealed inflammatory changes, hyperechogenicity, and presence of lymph node around ulcers. Correspondingly, we calculated the sensitivity and specificity for diagnosing gastric\/duodenal ulcers and used the Fisher's exact and Mann\u2013Whitney U tests to compare the frequency of findings and gastroduodenal wall thicknesses in pediatric patients with gastric\/duodenal ulcers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 6 and 24 were diagnosed with gastric and duodenal ulcers, respectively. The sensitivities of direct and indirect findings were 60.0% (18\/30) and 80.0% (24\/30), respectively; the corresponding specificities were 98.1% (210\/214) and 97.2% (208\/214). The frequency of direct and indirect sonographic findings differed significantly between patients with gastric or duodenal ulcers (18\/30 versus 24\/30, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.002). Gastric and duodenal wall thicknesses were greater in patients with gastric (6.6\u2009\u00b1\u20092.6\u2009mm versus 3.6\u2009\u00b1\u20091.4\u2009mm; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.003) or duodenal ulcer (5.0\u2009\u00b1\u20091.4\u2009mm versus 2.2\u2009\u00b1\u20091.0\u2009mm; <jats:italic>P<\/jats:italic> &lt;.0001), respectively, than in those without.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The frequency of indirect finding was greater than that of direct finding in pediatric patients with gastric\/duodenal ulcers. Therefore, sonographers should carefully evaluate indirect findings around the stomach or duodenum.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15727","type":"journal-article","created":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T14:42:39Z","timestamp":1618929759000},"page":"457-469","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Diagnostic Accuracy of Ultrasound for Detecting Gastric or Duodenal Ulcers in Pediatric Patients"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9523-4077","authenticated-orcid":false,"given":"Takahiro","family":"Hosokawa","sequence":"first","affiliation":[{"name":"Department of Radiology Saitama Children's Medical Center  Saitama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Tanami","sequence":"additional","affiliation":[{"name":"Department of Radiology Saitama Children's Medical Center  Saitama 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