{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T06:15:27Z","timestamp":1768976127996,"version":"3.49.0"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T00:00:00Z","timestamp":1624579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To construct the reference intervals for the cardiac volume (CV) of normal fetuses between 14 and 40\u2009weeks of pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Low risk singleton pregnancies with normal fetuses were prospectively recruited to acquire 4D\u2010cardio\u2010spatiotemporal image correlation volume datasets (VDS). Subsequent off\u2010line analyses of VDS were anonymously performed to calculate CV using the Virtual Organ Computer\u2010aided AnaLysis technique. The reference intervals were established as a function of gestational age (GA), biparietal diameter (BPD), head circumference (HC), and estimated fetal weight (EFW) based on the best\u2010fitted models for both mean and standard deviation (SD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 668 VDS were successfully calculated for CV. The best\u2010fitted models for the means and SDs are as follow: 1) GA in week\u00a0=\u00a06.422\u2009+\u2009e<jats:sup>(\u2212100.653 \u00d7 GA)<\/jats:sup> (SD\u00a0<jats:italic>=<\/jats:italic>\u00a00.641\u2009\u2212\u2009(0.170\u2009\u00d7\u2009GA)\u2009+\u2009(0.009\u2009\u00d7\u2009GA<jats:sup>2<\/jats:sup>)). 2) BPD\u00a0=\u00a00.016\u2009\u00d7\u2009(BPD)<jats:sup>3.589<\/jats:sup> (SD\u00a0=\u00a02.663\u2009\u2212\u2009(1.410\u2009\u00d7\u2009BPD)\u2009+\u2009(0.224\u2009\u00d7 BPD<jats:sup>2<\/jats:sup>)). 3) HC\u00a0=\u00a00.00017\u2009\u00d7\u2009(HC)<jats:sup>3.537<\/jats:sup> (SD\u00a0=\u00a02.341\u2009\u2212\u2009(0.341\u2009\u00d7\u2009HC)\u2009+\u2009(0.015\u2009\u00d7\u2009HC<jats:sup>2<\/jats:sup>)). The CV progressively increased with advancing fetal age (GA) and size (BPD, HC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The reference intervals of CV, theoretically best representing cardiac size, in relation to GA, BPD, HC, and EFW were first established and <jats:italic>Z<\/jats:italic>\u2010score was readily calculated. These will be helpful in detection of cardiac abnormalities, especially those associated with cardiomegaly.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15768","type":"journal-article","created":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T12:00:50Z","timestamp":1624622450000},"page":"887-897","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Reference Intervals of Fetal Cardiac Volume Between 14 and 40\u2009Weeks of Gestation"],"prefix":"10.1002","volume":"41","author":[{"given":"Keooudone","family":"Thammavong","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine, Chiang Mai University  Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suchaya","family":"Luewan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine, Chiang Mai University  Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3389-6478","authenticated-orcid":false,"given":"Theera","family":"Tongsong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Faculty of Medicine, Chiang Mai University  Chiang Mai Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,6,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.65.1_Spec_No.20"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7443"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1999.18.12.807"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4498"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.02.028"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12568"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5250"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(85)90298-4"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1998.11010030.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.86.2.420"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-999333"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2011.30.9.1191"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.8961"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.15768","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T21:15:56Z","timestamp":1692998156000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.15768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,25]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1002\/jum.15768"],"URL":"https:\/\/doi.org\/10.1002\/jum.15768","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,25]]},"assertion":[{"value":"2021-04-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}