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ICP was measured using intracranial bolt monitor and CEUS was monitored through a cranial window. Various CEUS parameters were monitored at baseline, immediately post return of spontaneous circulation (ROSC), 1\u2009hour\u2010post ROSC, and 3\u2009hours post\u2010ROSC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was significant ICP correlation with wash\u2010out slope assessed by CEUS time intensity curve analysis at immediate post\u2010ROSC. At 3\u2009hours post\u2010ROSC there was also significant negative correlation between ICP and peak enhancement which may be due to the evolution of anoxic injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of CEUS in assessing disruption of cerebral hemodynamics and ICP post cardiac arrest will need future validation and comparison to other imaging modalities. The correlation between CEUS parameters and ICP may be due to the alterations in cerebral autoregulation that result from anoxic brain injury.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15825","type":"journal-article","created":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T14:30:51Z","timestamp":1631716251000},"page":"1425-1432","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Intracranial Pressure and Cerebral Hemodynamic Monitoring After Cardiac Arrest in Pediatric Pigs Using Contrast Ultrasound\u2010Derived Parameters"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7692-7097","authenticated-orcid":false,"given":"Samuel S.","family":"Shin","sequence":"first","affiliation":[{"name":"Department of Neurocritical Care Hospital of University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania  Philadelphia PA 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