{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T02:16:06Z","timestamp":1767838566735,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T00:00:00Z","timestamp":1631836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Lung ultrasound (LUS) might be comparable to chest computed tomography (CT) in detecting parenchymal and pleural pathology, and in monitoring interstitial lung disease. We aimed to describe LUS characteristics of patients during the hospitalization for COVID\u201019 pneumonia, and to compare the extent of lung involvement at LUS and chest\u2010CT with inflammatory response and the severity of respiration impairment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>During a 2\u2010week period, we performed LUS and chest CT in hospitalized patients affected by COVID\u201019 pneumonia. Dosages of high sensitivity C\u2010reactive protein (HS\u2010CRP), <jats:sc>d<\/jats:sc>\u2010dimer, and interleukin\u20106 (IL\u20106) were also obtained. The index of lung function (<jats:italic>P<\/jats:italic>\/<jats:italic>F<\/jats:italic> ratio) was calculated from the blood gas test. LUS and CT scoring were assessed using previously validated scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010six consecutive patients (3 women) underwent LUS 34\u2009\u00b1\u200914\u2009days from the early symptoms. Among them, 21 underwent CT on the same day of LUS. A fair association was found between LUS and CT scores (<jats:italic>R<\/jats:italic>\u00a0=\u00a00.45, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.049), which became stronger if the B\u2010lines score on LUS was not considered (<jats:italic>R<\/jats:italic>\u00a0=\u00a00.57, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.024). LUS B\u2010lines score correlated with IL\u20106 levels (<jats:italic>R<\/jats:italic>\u00a0=\u00a00.75, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.011), and the number of involved lung segments detected by LUS correlated with the <jats:italic>P<\/jats:italic>\/<jats:italic>F<\/jats:italic> ratio (<jats:italic>R<\/jats:italic>\u00a0=\u00a00.60, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.019) but not with HS\u2010CRP and <jats:sc>d<\/jats:sc>\u2010Dimer levels. No correlations were found between CT scores and inflammations markers or <jats:italic>P<\/jats:italic>\/<jats:italic>F<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with COVID\u201019 pneumonia, LUS was correlated with both the extent of the inflammatory response and the <jats:italic>P<\/jats:italic>\/<jats:italic>F<\/jats:italic> ratio.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15831","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T13:44:59Z","timestamp":1631886299000},"page":"1465-1473","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Lung Ultrasound in Patients With <scp>SARS\u2010COV<\/scp>\u20102 Pneumonia: Correlations With Chest Computed Tomography, Respiratory Impairment, and Inflammatory Cascade"],"prefix":"10.1002","volume":"41","author":[{"given":"Gerardina","family":"Fratianni","sequence":"first","affiliation":[{"name":"Department of Cardiology Istituto Auxologico Italiano IRCCS, Ospedale S. 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Luca  Milan"},{"name":"Dipartimento di Medicina e Chirurgia, Universit\u00e0 di Milano\u2010Bicocca  Milan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Facchetti","sequence":"additional","affiliation":[{"name":"Department of Radiology, ASST Spedali Civili di Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Pini","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Unit, ASST Spedali Civili di Brescia  Brescia Italy"},{"name":"Department of Clinical and Experimental Sciences University of Brescia  Brescia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Bosco","sequence":"additional","affiliation":[{"name":"Department of Cardiology Istituto Auxologico Italiano IRCCS, Ospedale S. 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