{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:23:37Z","timestamp":1790713417895,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T00:00:00Z","timestamp":1638489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the natural course of the fetal hyaloid artery (FHA) using Slow<jats:italic>flow<\/jats:italic>HD during pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One\u2010hundred and eighteen normal fetuses were studied longitudinally using Slow<jats:italic>flow<\/jats:italic>HD to assess the natural course of FHA at 18\u201321\u2009+\u20096, 28\u201331\u2009+\u20096, and after 35\u2009weeks of gestation. Blood flow of FHA with\/without its branches (BF) was evaluated using Slow<jats:italic>flow<\/jats:italic>HD, and the band of FHA without blood flow (Band) was identified in each gestational period. The natural course of FHA was classified into six types: Type A, not detected (ND) in each gestational period; Type B, Band at 18\u201321\u2009+\u20096\u2009weeks; Type C, Band at 18\u201321\u2009+\u20096 and 28\u201331\u2009+\u20096\u2009weeks; Type D, BF at 18\u201321\u2009+\u20096\u2009weeks; Type E, BF at 18\u201321 + 6\u2009weeks and Band at 28\u201331\u2009+\u20096\u2009weeks; Type F, BF at 18\u201321\u2009+\u20096 and 28\u201331\u2009+\u20096\u2009weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>BF, Band, and ND were 83.5, 15.5, and 1.0% at 18\u201321\u2009+\u20096\u2009weeks, 8.8, 15.5, and 75.7% at 28\u201331\u2009+\u20096\u2009weeks, and 0, 0, and 100% after 35\u2009weeks, respectively. Type A was 1.0%, Type B was 13.6%, Type C was 1.9%, Type D was 61.2%, Type E was 13.6%, and Type F was 8.7%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The presence of FHA blood flow before 30\u2009weeks of gestation should be regarded as a physiologic phenomenon in normal fetuses.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15911","type":"journal-article","created":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T11:52:35Z","timestamp":1638532355000},"page":"2259-2267","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Natural Course of Fetal Hyaloid Artery: <scp>Slow<i>flow<\/i>HD<\/scp> Longitudinal Study"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8835-8554","authenticated-orcid":false,"given":"Toshiyuki","family":"Hata","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Miyake Clinic  Minami\u2010ku Okayama Japan"},{"name":"Department of Perinatology and Gynecology Kagawa University Graduate School of Medicine  Miki Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Koyanagi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Miyake Clinic  Minami\u2010ku Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomomi","family":"Yamanishi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Miyake Clinic  Minami\u2010ku Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saori","family":"Bouno","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Miyake Clinic  Minami\u2010ku Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riko","family":"Takayoshi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Miyake Clinic  Minami\u2010ku Okayama Japan"},{"name":"Department of Perinatology and Gynecology Kagawa University Graduate School of Medicine  Miki Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahito","family":"Miyake","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Miyake Clinic  Minami\u2010ku Okayama Japan"},{"name":"Department of Perinatology and Gynecology Kagawa University Graduate School of Medicine  Miki Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14226"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-3782(85)90182-3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.166.3.3277246"},{"key":"e_1_2_6_5_1","first-page":"275","article-title":"In utero study of the eye on normal fetuses. Static ultrasonographic aspects and clinical implications","volume":"18","author":"Roussat B","year":"1995","journal-title":"J Fr Ophthalmol"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0223(200011)20:11<894::AID-PD949>3.0.CO;2-J"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10009-1603"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20393"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.22043"},{"key":"e_1_2_6_10_1","first-page":"2330","article-title":"Estimation of gestational age with ultrasonic measurement of the fetus in each trimester","volume":"35","author":"Iwamoto K","year":"1983","journal-title":"Acta Obstet Gynaecol Jpn"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.10123"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1995.06040233.x"},{"key":"e_1_2_6_13_1","volume-title":"Medical Ultrasound Safety","author":"AIUM","year":"1994"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15911","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.15911","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15911","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T07:26:34Z","timestamp":1698305194000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.15911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,3]]},"references-count":12,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1002\/jum.15911"],"URL":"https:\/\/doi.org\/10.1002\/jum.15911","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,3]]},"assertion":[{"value":"2021-09-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}