{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:30:08Z","timestamp":1747150208987,"version":"3.40.5"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T00:00:00Z","timestamp":1643760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>We aims to determine the relationship of amniotic fluid sludge (AFS) and\/or short cervical length (CL, \u226425\u2009mm) with a high rate of preterm birth in women after cervical cerclage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort study was conducted among singleton pregnancies after cervical cerclage between January 2018 and December 2021. A total of 296 patients who underwent transvaginal ultrasound to evaluate CL and the presence of AFS within 2\u2009weeks after cerclage were included. Pregnancy outcome after cerclage was analyzed in accordance with the presence of AFS and CL \u226425\u2009mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In patients with cerclage, AFS was an independent risk factor for preterm birth at &lt;28 and &lt;36\u2009weeks but not for preterm birth at &lt;32\u2009weeks, and CL \u226425\u2009mm was an independent risk factor for preterm birth at &lt;28, &lt;32, and &lt;36\u2009weeks. The Kaplan\u2013Meier analysis showed that the association between the presence of AFS and short gestational age at delivery was statistically significant in women with CL \u226425\u2009mm (log rank test, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.000). The Cox regression analysis showed that these results remained significant after adjusting for confounding factors (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.000). The negative linear relationships between AFS and CL (<jats:italic>R<\/jats:italic>\u00a0=\u00a0\u22120.454, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) also explained the outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>AFS and short cervix have a direct effect on pregnancies after cerclage. Mid\u2010trimester AFS can become a supplementary ultrasound index for detecting preterm birth after cerclage in pregnant women with a short cervix.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15952","type":"journal-article","created":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T08:15:07Z","timestamp":1643789707000},"page":"2687-2693","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Relationship of Amniotic Fluid Sludge and Short Cervix With a High Rate of Preterm Birth in Women After Cervical Cerclage"],"prefix":"10.1002","volume":"41","author":[{"given":"Yingmin","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Ultrasound Medicine The Third Affiliated Hospital of Guangzhou Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowen","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine The Third Affiliated Hospital of Guangzhou Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianyi","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine The Third Affiliated Hospital of Guangzhou Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingtao","family":"Li","sequence":"additional","affiliation":[{"name":"Guangzhou Medical Centre for Critical Pregnant Women, Key Laboratory for Major Obstetric Disease of Guangdong Province The Third Affiliated Hospital of Guangzhou Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5973-4522","authenticated-orcid":false,"given":"Zhiyi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Medicine The Third Affiliated Hospital of Guangzhou Medical University  Guangzhou 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