{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T08:58:29Z","timestamp":1765357109166,"version":"3.40.5"},"reference-count":10,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T00:00:00Z","timestamp":1647820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare maternal and perinatal outcomes in pregnancies with transient and persistent idiopathic polyhydramnios to those with normal amniotic fluid volume.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cohort study included subjects delivering a singleton pregnancy between January 1, 2015, and June 30, 2020, with sonography \u226526\u2009weeks' gestation demonstrating transient or persistent idiopathic polyhydramnios (amniotic fluid index [AFI] \u226524.0\u2009cm) or normal AFI (referent group). The primary maternal outcome was a composite of spontaneous preterm delivery &lt;37\u2009weeks, cesarean delivery for malpresentation, abnormal labor progress, or nonreassuring fetal status, operative vaginal delivery, hemorrhage requiring transfusion, and umbilical cord prolapse. The primary perinatal outcome was a composite of birthweight &gt;4500\u2009g, fetal or neonatal death, 5\u2010minute Apgar score &lt;7, and neonatal intensive care unit admission for &gt;24\u00a0hours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients with transient polyhydramnios (<jats:italic>n<\/jats:italic>\u00a0=\u00a0259) exhibited maternal outcomes similar to those of the referent group (<jats:italic>n<\/jats:italic>\u00a0=\u00a0435) but had significantly increased odds for the primary perinatal outcome (odds ratio [OR] 1.70, 95% confidence interval [CI] 1.15\u20132.53; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.008) and for birthweight \u22654500\u2009g (OR 8.70, 95% CI 1.89\u201340.0; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.005). Persistent polyhydramnios (<jats:italic>n<\/jats:italic>\u00a0=\u00a0176) was significantly associated with both the primary maternal (OR 1.93, 95% CI 1.27\u20132.95, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.002) and primary perinatal outcome (OR 2.15, 95% CI 1.40\u20133.30; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001), and individually with cesarean delivery for abnormal labor (OR 3.22, 95% CI 1.55\u20136.68; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.002) and birthweight \u22654500\u2009g (OR 8.97, 95% CI 1.84\u201343.6; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.007).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Transient idiopathic polyhydramnios does not impact maternal outcomes but is associated with increased odds of newborn birthweight &gt;4500\u2009g. Persistent polyhydramnios is associated with both adverse maternal and perinatal outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15974","type":"journal-article","created":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T10:10:04Z","timestamp":1647857404000},"page":"2859-2866","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Transient Idiopathic Polyhydramnios"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4575-2308","authenticated-orcid":false,"given":"Joseph R.","family":"Wax","sequence":"first","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics and Gynecology Maine Medical Center  Portland ME USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelina","family":"Cartin","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics and Gynecology Maine Medical Center  Portland ME USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy Y.","family":"Craig","sequence":"additional","affiliation":[{"name":"Maine Medical Center Research Institute  Scarborough ME USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G.","family":"Pinette","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics and Gynecology Maine Medical Center  Portland ME USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ogx.0000290349.58707.e0"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.07.016"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1571320"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.12578"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogoh.2017.02.014"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2016.1148126"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2016.02.018"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1992.02050321.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-0645-1136"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.02.028"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15974","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.15974","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15974","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T22:22:36Z","timestamp":1692656556000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.15974"}},"subtitle":["Maternal and Perinatal Outcomes"],"short-title":[],"issued":{"date-parts":[[2022,3,21]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["10.1002\/jum.15974"],"URL":"https:\/\/doi.org\/10.1002\/jum.15974","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"type":"print","value":"0278-4297"},{"type":"electronic","value":"1550-9613"}],"subject":[],"published":{"date-parts":[[2022,3,21]]},"assertion":[{"value":"2021-12-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}