{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:25:15Z","timestamp":1791289515872,"version":"4.3.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T00:00:00Z","timestamp":1650585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Umbilical vein flow (UVF) is reduced in fetal growth restriction (FGR). We compared absolute and size\u2010adjusted UVF (estimated fetal weight [EFW] and abdominal circumference [AC]) and rates of abnormal UVF parameters (&lt;10th percentile) among FGR fetuses meeting Delphi criteria (FGR\u2010D) against small for gestational age (SGA) fetuses and appropriate for gestational age (AGA) controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Absolute UVF, UVF\/EFW, and UVF\/AC were compared between 73 FGR pregnancies (35 FGR\u2010D, 38 SGA) and 108 AGA controls. Rates of abnormal UVF were compared to abnormal umbilical artery pulsatility index (UAPI). Independent samples <jats:italic>t<\/jats:italic>\u2010tests, Mann\u2013Whitney <jats:italic>U<\/jats:italic>, odds ratio (OR), chi\u2010squared, and Fisher's exact tests were used as appropriate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean absolute UVF was significantly decreased in FGR\u2010D compared to AGA (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.0147), but not between SGA and AGA fetuses. The incidence of both abnormal absolute UVF and UVF\/AC values (&lt;10th centile) was higher among late\u2010onset FGR fetuses versus AGA fetuses (UVF: OR 2.7, confidence interval [CI] 1.37\u20135.4; UVF\/AC: OR 2.73, CI 1.37\u20135.4). UVF was more frequently abnormal than UAPI and in only two fetuses were both Doppler values abnormal.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Absolute UVF is altered in late\u2010onset FGR, and most pronounced among FGR\u2010D. UVF may provide additional insight into fetal compromise in those affected by growth restriction.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15993","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T08:52:17Z","timestamp":1650617537000},"page":"173-183","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Umbilical Venous Volume Flow in Late\u2010Onset Fetal Growth Restriction"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6475-8238","authenticated-orcid":false,"given":"Odessa P.","family":"Hamidi","sequence":"first","affiliation":[{"name":"Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology University of Colorado School of Medicine  Aurora CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camille","family":"Driver","sequence":"additional","affiliation":[{"name":"Division of Maternal Fetal Medicine, 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