{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T03:22:20Z","timestamp":1775272940072,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,4,23]],"date-time":"2022-04-23T00:00:00Z","timestamp":1650672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>This retrospective study was designed to evaluate which lower urinary tract ultrasound parameter(s) could predict the results of invasive urodynamic testing which are the current reference standard in the evaluation of bladder dysfunction in children with spina bifida.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Fifty eight children with spina bifida undergoing video urodynamic evaluation and a renal bladder ultrasound as their standard of care were evaluated. Quantitative and qualitative ultrasound parameters were then correlated with the videourodynamic study results which served as the reference standard.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For bladders with ending storage pressures above 15\u2009cm H<jats:sub>2<\/jats:sub>O, there were increases in these ultrasound measured parameters: 1) bladder mass (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.00019), 2) bladder\/body mass ratio (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.0059), and 3) wall thickness (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.01). We defined the storage cost as the final storage pressure divided by the percentage of expected bladder capacity attained. These data were analyzed to compute receiver operating curves with assuming end storage pressures cutoff points of 15, 20, 30, and 40\u2009cm H<jats:sub>2<\/jats:sub>O. The optimal area under the curve was found for a bladder weight of 65 g and a pressure cutoff of 30\u2009cm H<jats:sub>2<\/jats:sub>O with a sensitivity of 75% with a specificity of 84%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Bladder weight is independent of luminal volume, can be normalized to body weight, and may serve as a clinically valuable tool for noninvasive screening to define a subset of patients with neurogenic bladder with a higher likelihood of having abnormal videourodynamic results.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.15995","type":"journal-article","created":{"date-parts":[[2022,4,23]],"date-time":"2022-04-23T09:13:04Z","timestamp":1650705184000},"page":"17-26","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Ultrasound\u2010Estimated Bladder Weight Correlates With Videourodynamic Studies in Neurogenic Bladder Dysfunction"],"prefix":"10.1002","volume":"42","author":[{"given":"Misun","family":"Hwang","sequence":"first","affiliation":[{"name":"Department of Radiology The Children's Hospital of Philadelphia  Philadelphia PA USA"},{"name":"The Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan J.","family":"Back","sequence":"additional","affiliation":[{"name":"Department of Radiology The Children's Hospital of Philadelphia  Philadelphia PA USA"},{"name":"The Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Van Batavia","sequence":"additional","affiliation":[{"name":"The Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"},{"name":"Division of Urology The Children's Hospital of Philadelphia  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Octavio","family":"Tierradentro\u2010Garcia","sequence":"additional","affiliation":[{"name":"Department of Radiology The Children's Hospital of Philadelphia  Philadelphia PA USA"},{"name":"The Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kassa","family":"Darge","sequence":"additional","affiliation":[{"name":"Department of Radiology The Children's Hospital of Philadelphia  Philadelphia PA USA"},{"name":"The Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3839-7106","authenticated-orcid":false,"given":"Stephen A.","family":"Zderic","sequence":"additional","affiliation":[{"name":"The Perelman School of Medicine at the University of Pennsylvania  Philadelphia PA USA"},{"name":"Division of Urology The Children's Hospital of Philadelphia  Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0764-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22247"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199707000-00024"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1997.272.6.R1960"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.LAB.0000021135.87203.92"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00477.2007"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.90749.2008"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2012.03.051"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0302-2838(01)00023-9"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.03.062"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(96)00059-3"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)62591-6"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-006-0376-y"},{"key":"e_1_2_7_15_1","unstructured":"MiloR JorgensenP Springer M.https:\/\/bionumbers.hms.harvard.edu\/bionumber.aspx?id=109719&ver=2&trm=bladder&org"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(91)90426-T"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)52091-1"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-004-2304-6"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)65178-4"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)36650-8"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)00182-5"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.12.036"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65590-5"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20834"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.11.096"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000112978.54300.03"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(81)90349-6"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)38389-1"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.03.127"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2022.03.016"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004670100042"},{"key":"e_1_2_7_32_1","first-page":"S22","article-title":"Automatic measurement of ultrasound\u2010estimated bladder weight (UEBW) from three\u2010dimensional ultrasound","volume":"7","author":"Chalana V","year":"2005","journal-title":"Rev Urol"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15995","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.15995","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.15995","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T18:48:33Z","timestamp":1692470913000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.15995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,23]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1002\/jum.15995"],"URL":"https:\/\/doi.org\/10.1002\/jum.15995","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,23]]},"assertion":[{"value":"2021-08-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}