{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:23:37Z","timestamp":1768566217080,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T00:00:00Z","timestamp":1653696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006599","name":"Focused Ultrasound Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006599","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>Up to 70% of limb amputees develop chronic postamputation neuropathic pain (CPANP) which includes phantom pain and residual limb neuropathic pain due to neuroma formation. CPANP often requires invasive procedures aimed at neuroma ablation. Five amputees received 6 noninvasive magnetic resonance\u2010guided high\u2010intensity\u2010focused ultrasound MRgHIFU treatments ExAblate\u00ae, Insightec, Tirat\u2010Carmel, Israel). Although ablative temperature (&gt;65\u00b0C) at the neuroma was reached in only 1 patient, pain intensity dropped from 5.7 at baseline to 4.3 and back to 5.6 at 3 and 6\u2009month follow\u2010up. Post\u2010treatment bone necrosis was demonstrated in 1 patient. Although no firm conclusion about the effectiveness of MRgHIFU for CPANP could be drawn, further studies are warranted.<\/jats:p>","DOI":"10.1002\/jum.16026","type":"journal-article","created":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T10:43:55Z","timestamp":1653734635000},"page":"3119-3124","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Feasibility of Magnetic Resonance\u2010Guided High\u2010Intensity\u2010Focused Ultrasound (MRgHIFU) Ablation of Stump Neuromas for the Relief of Chronic Postamputation Neuropathic Pain"],"prefix":"10.1002","volume":"41","author":[{"given":"Alicia","family":"Nachtigal","sequence":"first","affiliation":[{"name":"Department of Radiology Hillel\u2010Yaffe Medical Center  Hadera Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronen","family":"Cozakov","sequence":"additional","affiliation":[{"name":"Institute of Pain Medicine Rambam Health Care Campus  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anat","family":"Grinfeld","sequence":"additional","affiliation":[{"name":"Department of Radiology Rambam Health Care Campus  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"May","family":"Haddad","sequence":"additional","affiliation":[{"name":"Institute of Pain Medicine Rambam Health Care Campus  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3748-1349","authenticated-orcid":false,"given":"Elon","family":"Eisenberg","sequence":"additional","affiliation":[{"name":"Rappaport Faculty of Medicine Technion, Israel Institute of Technology  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmr.2013.09.001"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2007.11.005"},{"key":"e_1_2_5_4_1","volume-title":"Phantom Limb Pain","author":"Hanyu\u2010Deutmeyer AA","year":"2021"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001705"},{"key":"e_1_2_5_6_1","first-page":"121","article-title":"Postamputation pain: epidemiology, mechanisms, and treatment","volume":"6","author":"Hsu E","year":"2013","journal-title":"J Pain Res"},{"key":"e_1_2_5_7_1","first-page":"19","article-title":"Management of post\u2010amputation pain","volume":"103","author":"Modest JM","year":"2020","journal-title":"R I Med J"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S127157"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jfas.2019.09.003"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/papr.12400"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00132-020-04032-1"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21261"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/13645706.2017.1414063"},{"key":"e_1_2_5_14_1","unstructured":"White E (ed). 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