{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T03:30:07Z","timestamp":1771299007002,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T00:00:00Z","timestamp":1655683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2016J01646"],"award-info":[{"award-number":["2016J01646"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81600669"],"award-info":[{"award-number":["81600669"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the characteristic ultrasonographic findings of adenoid cystic carcinoma (ACC) in major salivary glands and identify the value of polar vessel in color Doppler flow imaging (CDFI) for the diagnosis of ACC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From January 2017 to December 2021, 76 patients with parotid and submandibular gland tumors, including 14 patients with ACC, as confirmed by surgery and histopathology, were enrolled. Their clinicopathologic information and ultrasound (US) features were recorded and analyzed. The performance of polar vessel in CDFI for differentiating ACC from non\u2010ACC (benign tumors and mucoepidermoid carcinoma [MEC]) was analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ACC in the major salivary gland was more likely to be associated with pain symptoms (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.027) and unclear borders and rough edges in grayscale US (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.002, .015, respectively) than benign tumors. Compared to MEC, ACC tended to feature a homogeneous internal echo (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.008). ACC of the major salivary gland had a significantly higher incidence of polar vessel sign than that of non\u2010ACC (benign tumors and MEC) (<jats:italic>P\u2009&lt;<\/jats:italic>\u00a0.0001, .0001, respectively). The polar vessel sign showed good performance in distinguishing between ACC and non\u2010ACC, with an area under the receiver operating characteristic curve of 0.857, a sensitivity of 71.4%, a specificity of 100%, and an accuracy of 94.7%. Positive predictive value and negative predictive value were calculated at 100% and 93.9%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The US sign of polar vessel has high diagnostic efficiency, and it may have important potential for use as a new complementary sign for the diagnosis of ACC in major salivary glands.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16043","type":"journal-article","created":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T08:13:47Z","timestamp":1655712827000},"page":"603-611","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Polar Vessel"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1064-3929","authenticated-orcid":false,"given":"Huan\u2010Zhong","family":"Su","sequence":"first","affiliation":[{"name":"Department of Ultrasound, The First Affiliated Hospital of Xiamen University, School of Medicine Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The First Affiliated Hospital of Xiamen University, School of Medicine Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Dong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The First Affiliated Hospital of Xiamen University, School of Medicine Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Long\u2010Cheng","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The First Affiliated Hospital of Xiamen University, School of Medicine Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5448-4504","authenticated-orcid":false,"given":"Shu\u2010Jing","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The First Affiliated Hospital of Xiamen University, School of Medicine Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Qing","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The First Affiliated Hospital of Xiamen University, School of Medicine Xiamen University  Xiamen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0525-4299","authenticated-orcid":false,"given":"Yi\u2010Ming","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, The First Affiliated Hospital of Xiamen University, School of Medicine Xiamen University  Xiamen China"},{"name":"Department 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