{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:23:27Z","timestamp":1788211407157,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,9,3]],"date-time":"2022-09-03T00:00:00Z","timestamp":1662163200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>Subacute thyroiditis (SAT) is a self\u2010limiting, inflammatory thyroid disease possibly caused by viral infection. In recent years, the incidence of SAT is increasing, especially during the pandemic of the COVID\u201019. This study aimed to evaluate the efficacy, safety, and recovery time of capsular thyroid injection therapy under ultrasound guidance for SAT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 73 patients with SAT were divided into two groups. Patients in group A (n\u00a0=\u00a048) received an ultrasound\u2010guided capsular injection consisting of dexamethasone (DEX) and lidocaine in the thyroid lesion area, while patients in group B (n\u00a0=\u00a025) received oral prednisolone (PSL). The two groups were compared for pain relief and treatment duration, the recovery time of thyroid function, recurrence rates, hypothyroidism incidence, and drug\u2010related side effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The follow\u2010up time was 1\u2009year. In group A, the duration of pain relief, treatment, and recovery time of thyroid function were significantly shorter than that in group B (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05), and no statistically significant differences in recurrence rate or incidence of hypothyroidism were observed (<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.05). Weight gain was significantly higher in group A at the end of treatment (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared with oral PSL treatment, ultrasound\u2010guided local injection of DEX and lidocaine into the capsular thyroid is a safe and effective procedure that can significantly reduce the treatment time of SAT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16054","type":"journal-article","created":{"date-parts":[[2022,9,3]],"date-time":"2022-09-03T14:00:12Z","timestamp":1662213612000},"page":"613-621","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Ultrasound\u2010Guided Capsular Thyroid Injection Therapy With Dexamethasone and Lidocaine Mixture for Subacute Thyroiditis"],"prefix":"10.1002","volume":"42","author":[{"given":"Jinlong","family":"Huo","sequence":"first","affiliation":[{"name":"Department of General Surgery, Digestive Disease Hospital Affiliated Hospital of Zunyi Medical University  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Qu","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youming","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuanghong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2234-4854","authenticated-orcid":false,"given":"Dong","family":"Ou","sequence":"additional","affiliation":[{"name":"Department of Oncology The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi)  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Digestive Disease Hospital Affiliated Hospital of Zunyi Medical University  Zunyi China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,3]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Endotext","author":"Hennessey J","year":"2000"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021799"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpem.2003.16.6.897"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992288902800403"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03345675"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.00047"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.47.0740"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/794943"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.7860\/JCDR\/2015\/14893.6427"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0459"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-016-1122-3"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-020-04337-8"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201801226R"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2019.01.047"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S188193"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2014.03.013"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2017.93.6.322"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.5812\/aapm.32101"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaa276"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42000-020-00230-w"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9020534"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2019.01.07"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2016.06.009"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1157\/13110315"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-017-0983-6"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.27675"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.33520"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000018564"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.16054","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.16054","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.16054","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T12:11:40Z","timestamp":1709813500000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.16054"}},"subtitle":["A Single\u2010Center Study"],"short-title":[],"issued":{"date-parts":[[2022,9,3]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["10.1002\/jum.16054"],"URL":"https:\/\/doi.org\/10.1002\/jum.16054","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,3]]},"assertion":[{"value":"2022-03-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}