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The same radiologist performed all ultrasound examinations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>For clinic features, TCs tended to occur in females compared with ECs (66.7 vs 28.5%; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). In addition, TCs were prone to occur in the hairy area compared with ECs (77.8 vs 13.1%; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). For ultrasound features, the internal hyperechogenicity and cystic change were more likely to appear in TCs in comparison with ECs (92.6 vs 25.5%; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001; 70.4 vs 23.4%; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001, respectively). Upon the features mentioned above, a prediction model was established with the areas under the receiver operating characteristic curves of 0.936 and 0.864 in the pilot and validation cohorts, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>US is promising for differentiating TCs from ECs and is valuable for their clinical management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16211","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T08:18:08Z","timestamp":1678436288000},"page":"1941-1950","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The Value of Ultrasound for Differentiating Trichilemmal Cysts From Epidermoid Cysts"],"prefix":"10.1002","volume":"42","author":[{"given":"Wei\u2010Wei","family":"Ren","sequence":"first","affiliation":[{"name":"Department of Medical Ultrasound, Shanghai Tenth People's Hospital Tongji University  Shanghai 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