{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:12:33Z","timestamp":1793707953886,"version":"4.6.1"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T00:00:00Z","timestamp":1682985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the application value of contrast\u2010enhanced ultrasonography (CEUS) in ultrasound\u2010guided lauromacrogol injections in patients with cesarean scar pregnancies (CSP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 31 patients diagnosed with CSP, who underwent an ultrasound\u2010guided lauromacrogol injection + curettage in our hospital between February 2019 and December 2020 and had a complete recovery confirmed by a postoperative ultrasound review and serum \u03b2\u2010human chorionic gonadotropin (\u03b2\u2010hCG) assay, were enrolled as the study subjects. According to the volume of intraoperative blood loss and the duration of postoperative vaginal bleeding, the patients were divided into two groups, with 19 in the significantly effective group (Group A) and 12 in the effective group (Group B). The recorded clinical data, including age, duration of amenorrhea, number of pregnancies, number of deliveries, time since last cesarean delivery, number of cesarean deliveries, and preoperative serum \u03b2\u2010hCG levels, were retrospectively analyzed. The morphological indicators in CEUS before the lauromacrogol injection, as well as immediately and 12\u201324\u2009hours after the injection, were compared between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In Group A, the post\u2010injection CEUS showed no enhancement, single strip enhancement, and sparse punctate enhancement, while in Group B, it showed a more irregular ring and local patch enhancement. In addition, the number of cases where the CEUS showed no enhancement 12\u201324\u2009hours after the injection was more than that of the immediate CEUS after the injection. In Group A, four (21.1%) cases showed a single strip\u2010like blood flow on the immediate postoperative CEUS, four (21.1%) cases showed a sparsely dotted blood flow on the immediate postoperative CEUS, and three cases turned into no enhancement 12\u201324\u2009hours after the injection. A total of four cases in Group B showed that the contrast enhancement range 12\u201324\u2009hours after the injection was reduced compared with that of the immediate contrast after the injection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Contrast\u2010enhanced ultrasonography can guide the location selection of the lauromacrogol injection in patients with CSP, and its postoperative morphological indicators can adequately predict the therapeutic effect after curettage and guide clinical management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16236","type":"journal-article","created":{"date-parts":[[2023,5,2]],"date-time":"2023-05-02T11:13:12Z","timestamp":1683025992000},"page":"2125-2133","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Application Value of Contrast\u2010Enhanced Ultrasonography in Assessing the Efficacy of Ultrasound\u2010Guided Lauromacrogol Injections in 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