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Genetics, age, and environmental factors determine the progression of the disease. DIE manifests with numerous symptoms, which are similar to unrelated diseases, namely dysmenorrhea, dyspareunia, urinary tract infections, and infertility. Transvaginal ultrasound, magnetic resonance imaging, computed tomography, and physical examination may detect and differentiate endometriosis lesions from other diseases. Its clinical management typically involves laparoscopic surgery and hormonal therapy. These are designed to improve the quality of life and to address individual reproductive goals. This pictorial essay aims to provide clinical cases to highlight the characteristic radiological findings in each diagnostic modality and in addition to elucidate the current clinical management of DIE.<\/jats:p>","DOI":"10.1002\/jum.16318","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T13:19:20Z","timestamp":1692019160000},"page":"2897-2904","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Deep Infiltrating Endometriosis"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1205-5426","authenticated-orcid":false,"given":"Abdullah","family":"Nadeem","sequence":"first","affiliation":[{"name":"Department of Medicine Dow University of Health Sciences  Karachi 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