{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:10:53Z","timestamp":1780733453030,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to evaluate the nail units of patients with axial spondyloarthritis (ax\u2010SpA) using ultrasound and to identify any subclinical changes. We also aimed to examine the relationship between clinical enthesitis scores and nail involvement in patients with ax\u2010SpA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included 40 patients with ax\u2010Spa, 40 patients with psoriatic arthritis (PsA), and 40 healthy controls. The thickness of the nail plates, morphological changes, the thickness of the proximal nail units, the thickness of the nail beds, and power Doppler signal intensities were evaluated and compared. Maastricht Ankylosing Spondylitis Enthesitis Score and Spondyloarthritis Research Consortium of Canada Enthesitis Index were also evaluated in patients with ax\u2010SpA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference between the thickness of the nail plates of the three groups (<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.05). The first nail bed thickness of ax\u2010SpA cases was significantly higher than the control group (<jats:italic>P<\/jats:italic>\u2009=\u2009.046), and the fourth and fifth nail proximal unit thicknesses of the control group were significantly lower than the ax\u2010SpA and PsA groups (<jats:italic>P<\/jats:italic>\u2009=\u2009.023, <jats:italic>P<\/jats:italic>\u2009=\u2009.017). We also found that the Wortsman scores of the cases with PsA were significantly higher than the ax\u2010SpA and control groups (<jats:italic>P<\/jats:italic>\u2009=\u2009.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The thickness of the proximal nail unit adjacent to the insertion of the digital extensor tendon, which is considered as the enthesis area, is similar to the patients with PsA in patients with ax\u2010SpA, especially in the fourth and fifth fingers compared to the control group. On the other hand, almost no structural changes in nail plates were observed in patients with ax\u2010SpA group.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16426","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T09:42:29Z","timestamp":1707298949000},"page":"967-978","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ultrasonographic Evaluation of Nail Involvement in Patients With Axial Spondyloarthritis"],"prefix":"10.1002","volume":"43","author":[{"given":"Bilal","family":"Kulaks\u0131z","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2882-2578","authenticated-orcid":false,"given":"Deniz","family":"Palamar","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4378-5907","authenticated-orcid":false,"given":"Tugce Ozekli","family":"Misirlioglu","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0346-1473","authenticated-orcid":false,"given":"Kenan","family":"Akgun","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8202-0931","authenticated-orcid":false,"given":"Rana","family":"Terlemez","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Cerrahpasa Medical Faculty Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00393-009-0510-y"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2017.188"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1586\/1744666X.2016.1146133"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-016-1093-z"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kel214"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0000000000000054"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm7120546"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000343607"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.2.127"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.084244"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.100826"},{"key":"e_1_2_7_13_1","first-page":"2286","article-title":"A new approach to defining disease status in ankylosing spondylitis: the Bath ankylosing spondylitis disease activity index","volume":"21","author":"Garrett S","year":"1994","journal-title":"J Rheumatol"},{"key":"e_1_2_7_14_1","first-page":"2281","article-title":"A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath ankylosing spondylitis functional index","volume":"21","author":"Calin A","year":"1994","journal-title":"J Rheumatol"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.1.20"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-010-1623-z"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19095611"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.686470"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-018-4160-8"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.11152\/mu-1327"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15035"},{"key":"e_1_2_7_22_1","first-page":"1097","article-title":"Ultrasound assessment of changes in nails in psoriasis and psoriatic arthritis","volume":"825","author":"Krajewska\u2010W\u0142odarczyk M","year":"2018","journal-title":"Biomed Res Int"},{"key":"e_1_2_7_23_1","first-page":"137","article-title":"Ultrasound anatomy of normal nails unit with 18 MHz linear transducer","volume":"114","author":"Cecchini A","year":"2009","journal-title":"Ital J Anat Embryol"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-022-02404-5"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.11152\/mu.2013.2066.183.hgh"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-018-4222-y"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-019-04437-0"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrnm.2015.04.009"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40477-017-0253-6"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-012-1274-9"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42358-021-00207-2"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.16426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T06:34:00Z","timestamp":1713335640000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.16426"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,7]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1002\/jum.16426"],"URL":"https:\/\/doi.org\/10.1002\/jum.16426","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,7]]},"assertion":[{"value":"2023-10-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}