{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:14:32Z","timestamp":1790907272593,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to assess the effectiveness of the Global OMERACT\u2013EULAR Synovitis Score (GLOESS) of bilateral second to fifth metacarpophalangeal joints (MCP 2\u20135) in evaluating rheumatoid arthritis (RA) activity in a real\u2010life setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study included consecutive RA patients without hyperalgesia. Clinical data were extracted from electronic medical records. Evaluations were conducted on bilateral MCP 2\u20135 by two independent experts in musculoskeletal ultrasound (MSUS). Correlation between clinical and ultrasonographic parameters was analyzed, aiming to define a cutoff value for detecting disease activity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010nine patients were included. The mean DAS28\u2010ESR was 4.3 (\u00b11.4), and the median GLOESS was 7 (13). The correlation between GLOESS and DAS28 was moderate (<jats:italic>r<\/jats:italic>\u2009=\u2009.62; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). A total GLOESS score of \u22643 and all joints with both GS and PD \u22641 showed good sensitivity and specificity for detecting disease activity (remission\/low vs moderate\/high, <jats:italic>P<\/jats:italic>\u2009=\u20090).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In a real\u2010life scenario, GLOESS for MCP 2\u20135 emerges as a valuable measure of RA activity. The optimal cutoff distinguishing remission\/low from moderate\/high disease activity was determined to be GLOESS \u22643, with all MCP joints exhibiting both GS and PD scores of \u22641.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16455","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T13:28:46Z","timestamp":1711978126000},"page":"1313-1318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["How Does Ultrasound Global OMERACT\u2013EULAR Synovitis Score (GLOESS) for Rheumatoid Arthritis (RA) Activity Assessment Perform in Real\u2010Life?"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1090-3708","authenticated-orcid":false,"given":"Nicole Pamplona Bueno","family":"de Andrade","sequence":"first","affiliation":[{"name":"Servi\u00e7o de Reumatologia Hospital de Cl\u00ednicas de Porto Alegre (HCPA)  Porto Alegre Brazil"},{"name":"Faculdade de Medicina Universidade Federal do Rio Grande do Sul (UFRGS)  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claiton Viegas","family":"Brenol","sequence":"additional","affiliation":[{"name":"Faculdade de Medicina Universidade Federal do Rio Grande do Sul (UFRGS)  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael Mendon\u00e7a","family":"da Silva Chakr","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Reumatologia Hospital de Cl\u00ednicas de Porto Alegre (HCPA)  Porto Alegre Brazil"},{"name":"Faculdade de Medicina Universidade Federal do Rio Grande do Sul (UFRGS)  Porto Alegre Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-203158"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10877"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20939"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22190"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2016-000428"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207709"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-017-3662-1"},{"key":"e_1_2_7_9_1","first-page":"811","article-title":"Evaluaci\u00f3n de cambios ultrasonogr\u00e1ficos tempranos con el sistema de puntuaci\u00f3n Global OMERACT\u2010EULA (GLOESS) en pacientes con artritis reumatoide que inician tratamiento con inhibidores del 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methotrexate in early rheumatoid arthritis, TOVERA \u2013 a longitudinal study","volume":"72","author":"Stoenoiu M","year":"2020","journal-title":"Arthritis Rheumatol"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2022-eular.561"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kep458"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.181095"},{"key":"e_1_2_7_20_1","first-page":"614","article-title":"Biostatistics 104: correlational analysis","volume":"44","author":"Chan YH","year":"2003","journal-title":"Singapore Med J"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2015-000237"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37954"},{"key":"e_1_2_7_23_1","first-page":"117","article-title":"Ultrasound changes following controlled mechanical stress in synovial tissue in the hands of healthy individuals","volume":"1","author":"Guill\u00e9n\u2010Astete CA","year":"2022","journal-title":"ARP Rheumatol"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-017-3925-x"}],"container-title":["Journal of Ultrasound in 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