{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T16:56:48Z","timestamp":1767373008029,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T00:00:00Z","timestamp":1721347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2024,10]]},"abstract":"Objectives<\/jats:title>To investigate the prevalence of oligohydramnios, brain sparing, and cardiac dysfunction\u00a0among a cohort of fetal growth restriction (FGR).<\/jats:p><\/jats:sec>Methods<\/jats:title>To assess the prevalence of oligohydramnios amongst a large sample of FGR fetuses, we screened a database of ultrasounds of FGR pregnancies from our maternal\u2010fetal medicine clinics (clinical cohort) for diminished amniotic fluid volume. Using a threshold of a maximum vertical pocket (MVP) of <2\u2009cm for \u201coligohydramnios,\u201d and 2 to 3\u2009cm as a \u201creduced fluid\u201d group, trends of Doppler values and cardiac parameters were assessed from pregnancies in an ongoing research study (comprehensive cohort).<\/jats:p><\/jats:sec>Results<\/jats:title>In the clinical cohort, oligohydramnios was identified in only 2\/229 (0.8%) and reduced fluid in 19\/229 (8%). In the comprehensive cohort, oligohydramnios was seen in 3\/126 (2.3%) and reduced fluid in 14\/126 (11.1%). A high rate of cardiac and Doppler abnormalities were observed in the oligohydramnios group of the comprehensive cohort. The patients with oligohydramnios had a distinctly different cardiac phenotype with small (2\/3 with cardiac area\u2009<5th%) (P<\/jats:italic>\u2009=\u20090.01) and round (3\/3 with global sphericity index\u2009<5th%) (P<\/jats:italic>\u2009=\u20090.02) hearts.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Oligohydramnios, when present with FGR, is accompanied by high rates of cerebral and cardiovascular abnormalities.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16531","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T12:44:08Z","timestamp":1721393048000},"page":"1969-1978","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of Amniotic Fluid Volume and Fetal Cardiac and Cerebrovascular Parameters in Fetal Growth Restriction"],"prefix":"10.1002","volume":"43","author":[{"given":"Lauren","family":"Sayres","sequence":"first","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics and Gynecology University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5591-2931","authenticated-orcid":false,"given":"Roopjit K.","family":"Sahi","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics and Gynecology University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Straub","sequence":"additional","affiliation":[{"name":"Division of Maternal\u2010Fetal Medicine, Department of Obstetrics and Gynecology University of Colorado School of Medicine Aurora Colorado 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