{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T13:27:21Z","timestamp":1788355641832,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the influence of different measurement conditions and ultrasound training level on uterine artery pulsatility index (UtA\u2010PI) measurements as required for combined first trimester preeclampsia (PE) screening.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective study of consecutive patients with singleton pregnancies presenting for an ultrasound examination between 11 and 14\u2009weeks' gestation. UtA\u2010PI measurements were conducted by residents in training and repeated by experienced sonographers thereafter. UtA\u2010PI measurements were conducted under different examination conditions. First, the trainee sonographers performed transabdominal sagittal and transverse UtA\u2010PI measurements without bladder filling. These measurements were then repeated by the expert sonographers. Additionally, the expert sonographers also performed transvaginal UtA\u2010PI measurements and transabdominal measurements with bladder filling. Statistical analysis was conducted with the statistical software R and included descriptive statistics as well as 2\u2010sided paired <jats:italic>t<\/jats:italic> tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 100 women were included in the study. Mean age was 31.7\u2009\u00b1\u20094.92\u2009years and mean gestational week was 12.5\u2009\u00b1\u20090.53\u2009weeks. A total of 56% were nulliparous and 44% were parous. UtA\u2010PI was significantly lower if performed by a sonographer in training versus an experienced sonographer (<jats:italic>P<\/jats:italic>\u2009=\u2009.031). No significant difference was observed in comparing transverse and sagittal techniques (<jats:italic>P<\/jats:italic>\u2009=\u2009.241). There was also no significant difference in transabominal versus transvaginal measurements (<jats:italic>P<\/jats:italic>\u2009=\u2009.806) and with an empty versus full bladder (<jats:italic>P<\/jats:italic>\u2009=\u2009.444).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Experience of sonographer has a significant impact on UtA\u2010PI. Supervised onsite training is necessary to improve reliability and consistency of UtA\u2010PI measurements and make PE screening reliable for implementation in a universal screening setting.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16572","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T06:49:21Z","timestamp":1725950961000},"page":"2375-2383","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Impact of Sonographer Experience, Insonation Angle, and Bladder Filling on Uterine Artery Doppler Measurements in the First Trimester of Pregnancy"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2805-1200","authenticated-orcid":false,"given":"Sabrina","family":"Einig","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Prenatal Medicine, Division of Gynecologic and Prenatal Ultrasound University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Monod","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Prenatal Medicine, Division of Gynecologic and Prenatal Ultrasound University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Baumann","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Prenatal Medicine, Division of Gynecologic and Prenatal Ultrasound University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annkathrin","family":"Butensch\u00f6n","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Prenatal Medicine, Division of Gynecologic and Prenatal Ultrasound University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmin","family":"Engesser\u2010Mussbah","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Prenatal Medicine, Division of Gynecologic and Prenatal Ultrasound University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubertina","family":"Reina","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Prenatal Medicine, Division of Gynecologic and Prenatal Ultrasound University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Schoetzau","sequence":"additional","affiliation":[{"name":"Department of Biomedicine University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Mosimann","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Prenatal Medicine, Division of Gynecologic and Prenatal Ultrasound University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwendolin","family":"Manegold\u2010Brauer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Prenatal Medicine, Division of Gynecologic and Prenatal Ultrasound University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2016.02.001"},{"key":"e_1_2_9_3_1","first-page":"103","article-title":"Competing risks model in screening for preeclampsia by maternal factors and biomarkers at 11\u201313\u2009weeks gestation","volume":"214","author":"O'Gorman N","year":"2016","journal-title":"Am J Obstet Gynecol"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000341264"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000338470"},{"key":"e_1_2_9_6_1","article-title":"First trimester combined screening for preeclampsia and small for gestational age\u2014a single centre experience and validation of the FMF screening algorithm","volume":"147","author":"Mosimann B","year":"2017","journal-title":"Swiss Med Wkly"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.13275"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e3181e9322a"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.11.561"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000336662"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1704559"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.18816"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.12.016"},{"key":"e_1_2_9_14_1","doi-asserted-by":"crossref","unstructured":"TrottmannF ChallandeP Manegold\u2010BrauerG et al.Implementing preeclampsia screening in Switzerland (IPSISS)\u2014first results from a multicentre registry.Fetal Diagn Ther.2023.","DOI":"10.1159\/000533201"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.10.024"},{"key":"e_1_2_9_16_1","unstructured":"The Fetal Medicine Foundation.FMF guidelines.2023.https:\/\/fetalmedicine.org\/education\/preeclampsia-screening."},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12366"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.23698"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4970"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14762"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.18917"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S228619"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000366060"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2017.1341481"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.3109\/10641955.2010.506232"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14732"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.16572","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T11:37:22Z","timestamp":1731497842000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.16572"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,9]]},"references-count":25,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/jum.16572"],"URL":"https:\/\/doi.org\/10.1002\/jum.16572","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,9]]},"assertion":[{"value":"2024-06-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}