{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:36:34Z","timestamp":1790375794309,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T00:00:00Z","timestamp":1737936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To determine the efficacy of quantitative shear wave elastography in differentiating benign and malignant axillary lymph nodes (ALN).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Exactly 127 lymph nodes from 127 patients with clinically palpable axillary swelling were examined by both B\u2010mode sonography and elastography from November 2022 to March 2024. Gray\u2010scale sonograms were evaluated based on: the short\u2010axis diameter, shape, hilum, maximum cortical thickness, and border of the ALN. Shear wave elastography determined the mean elasticity modulus (<jats:italic>E<\/jats:italic>\u2010mean) and elasticity ratio (<jats:italic>E<\/jats:italic>\u2010ratio). Fine needle aspiration cytology or histopathological examination was kept as the gold standard and diagnostic performance shear wave elastography was compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The data showed that out of 127 lymph nodes, 77 (60.6%) were benign and 50 (39.4%) were malignant based on pathological results. The <jats:italic>E<\/jats:italic>\u2010mean for malignant lymph nodes (mean, 73.15\u2009kPa) was higher than that for benign lymph nodes (mean, 21.47\u2009kPa; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). The area under the receiver operating characteristic curve for <jats:italic>E<\/jats:italic>\u2010ratio in predicting malignant and benign lymph nodes was 0.897 (95% CI: 0.839\u20130.955). The <jats:italic>E<\/jats:italic>\u2010ratio for malignant lymph nodes was also higher (mean, 10.2) than for benign nodes (mean, 2.95; <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). The area under the receiver operating characteristic curve for <jats:italic>E<\/jats:italic>\u2010ratio in predicting malignant and benign lymph nodes was 0.816 (95% CI: 0.733\u20130.899).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results showed a significant association between tissue elasticity and pathological correlation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16653","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T13:56:22Z","timestamp":1737986182000},"page":"935-944","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Shear Wave Elastography as a Supplement Tool in Differentiating Benign and Malignant Axillary Lymph Nodes"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0459-6155","authenticated-orcid":false,"given":"Aishwarya","family":"Sharma","sequence":"first","affiliation":[{"name":"Department 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