{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:09:47Z","timestamp":1782439787499,"version":"3.54.5"},"reference-count":60,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T00:00:00Z","timestamp":1745884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005230","name":"Natural Science Foundation of Chongqing Municipality","doi-asserted-by":"publisher","award":["CSTB2022NSCQ\u2010MSX0140"],"award-info":[{"award-number":["CSTB2022NSCQ\u2010MSX0140"]}],"id":[{"id":"10.13039\/501100005230","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the effect of ovarian endometriotic cysts on the efficacy of high intensity focused ultrasound (HIFU) in patients with adenomyosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Based on magnetic resonance imaging (MRI) findings, patients were categorized into three groups according to the presence and type of adnexal cyst signal: group A (with endometriotic cyst signal), group B (with simple cyst signal), and group C (without cyst signal). The non\u2010perfused volume ratio (NPVR), postoperative dysmenorrhea scores, and long\u2010term recurrence of HIFU were compared among groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 396 patients were enrolled, comprising group A (77 cases), group B (134 cases), and group C (185 cases), and the NPVR were 41.83, 44.99, and 50.79%, respectively (<jats:italic>P<\/jats:italic>\u2009=\u2009.021). The postoperative dysmenorrhea scores were 3 (2, 5), 2 (1, 4), and 2 (1, 4) (<jats:italic>P<\/jats:italic>\u2009=\u2009.012), while the pregnancy rates were 20.00%, 27.27%, and 43.59%, respectively (<jats:italic>P<\/jats:italic>\u2009=\u2009.072). Cumulative recurrence rates for patients with endometriotic cysts at 1, 2, 3, 5, and 10\u2009years were 45.60, 56.10, 57.90, 61.90, and 67.30%, respectively (log\u2010rank <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). Endometriotic cysts were significantly associated with higher dysmenorrhea scores and represented an independent risk factor for postoperative pregnancy (OR\u2009=\u20090.338, 95% CI: 0.129\u20130.886, <jats:italic>P<\/jats:italic>\u2009=\u2009.027) and long\u2010term recurrence (HR\u2009=\u20091.865, 95% CI: 1.275\u20132.728, <jats:italic>P<\/jats:italic>\u2009=\u2009.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The signal of endometriotic cyst on MRI exhibits a negative correlation with the efficacy of HIFU in patients with adenomyosis. Preoperative MRI assessment of adnexal cyst signal in patients facilitates the development of a more tailored and comprehensive treatment plan for individuals suffering from adenomyosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jum.16714","type":"journal-article","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T08:35:34Z","timestamp":1745915734000},"page":"1609-1622","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Ovarian Endometriotic Cyst on the Efficacy of High Intensity Focused Ultrasound for Adenomyosis"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3398-946X","authenticated-orcid":false,"given":"Jinfeng","family":"Lin","sequence":"first","affiliation":[{"name":"State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering Chongqing Medical University  Chongqing China"},{"name":"Department of Gynecology Yangjiang 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