{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T04:07:35Z","timestamp":1771042055285,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aims to evaluate the diagnostic value of a novel multimodal approach combining transperineal ultrasound (TPUS), transrectal dual\u2010plane ultrasound, and shear wave elastography (SWE) in predicting stress urinary incontinence (SUI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 70 women diagnosed with SUI and 110 healthy controls were included. Clinical data such as age, body mass index (BMI), mode of delivery, and relevant medical history were collected. Pelvic floor ultrasound was performed using TPUS and transrectal dual\u2010plane ultrasound. Key parameters, including bladder neck mobility, urethral rotation angle, urethral length, and urethral stiffness measured by SWE, were recorded and analyzed. Statistical analysis was conducted using SPSS version 27.0, and a multifactorial predictive model was developed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Significant differences were observed between the SUI and control groups in bladder neck mobility (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.034), urethral rotation angle (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.059), and urethral stiffness measured by SWE (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001). The average Young's modulus of the urethral sphincter was significantly lower in the SUI group (39.22\u2009\u00b1\u20095.83\u2009kPa) compared to the control group (52.11\u2009\u00b1\u20099.24\u2009kPa). Age and average urethral sphincter elasticity were identified as independent risk factors for SUI. The multifactorial model demonstrated high clinical applicability with an AUC of 0.891 (sensitivity: 84%, specificity: 80%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The combination of TPUS, transrectal dual\u2010plane ultrasound, and SWE provides a reliable, non\u2010invasive diagnostic tool for predicting SUI. The study highlights the importance of urethral stiffness and bladder neck mobility in the pathophysiology of SUI. This multi\u2010modal approach shows strong potential for early detection and personalized treatment strategies. This multimodal approach offers a non\u2010invasive, reliable tool for early SUI detection and personalized management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jum.70099","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T12:50:50Z","timestamp":1762779050000},"page":"621-630","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Multimodal Ultrasound Approach Combining Transperineal and Transrectal Shear Wave Elastography for Early Prediction of Stress Urinary Incontinence in Women"],"prefix":"10.1002","volume":"45","author":[{"given":"Yidan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Ultrasonography Nanjing First Hospital, Nanjing Medical University  Nanjing People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Gynecology Nanjing First Hospital, Nanjing Medical University  Nanjing People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyan","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Gynecology Nanjing First Hospital, Nanjing Medical University  Nanjing People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gynecology Nanjing First Hospital, Nanjing Medical University  Nanjing People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaping","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Nanjing First Hospital, Nanjing Medical University  Nanjing People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujuan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gynecology Nanjing First Hospital, Nanjing Medical University  Nanjing People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiajun","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Ultrasonography Nanjing First Hospital, Nanjing Medical University  Nanjing People's Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1914037"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2017.12.008"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-009-0976-9"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)00348-4"},{"key":"e_1_2_6_6_1","first-page":"113","article-title":"Standardisation of ambulatory urodynamic monitoring: report of the standardisation sub\u2010committee of the International Continence Society for Ambulatory Urodynamic Studies","volume":"19","author":"Waalwijk van Doorn E","year":"2000","journal-title":"NeurourolUrodyn"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1389.034"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-88740-4"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14222549"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1677-5538.ibju.2020.1100"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.18650"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.25080"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000526"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24877"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2018.10.034"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fjurol.2024.102848"},{"key":"e_1_2_6_17_1","first-page":"343","article-title":"Factors maintaining the intraurethral pressure in women","volume":"17","author":"Rud T","year":"1980","journal-title":"Invest Urol"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15255"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13688"},{"key":"e_1_2_6_20_1","first-page":"CD005654","article-title":"Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women","volume":"10","author":"Dumoulin C","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_21_1","doi-asserted-by":"crossref","unstructured":"PtaszkowskiK Ma\u0142kiewiczB ZdrojowyR et al.Assessment of the elastographic and electromyographic of pelvic floor muscles in postmenopausal women with stress urinary incontinence symptoms.2021;11:2051.","DOI":"10.3390\/diagnostics11112051"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2019.08.015"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-015-2916-1"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0000000000000386"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.70099","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.70099","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.70099","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T03:40:14Z","timestamp":1771040414000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.70099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/jum.70099"],"URL":"https:\/\/doi.org\/10.1002\/jum.70099","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,10]]},"assertion":[{"value":"2025-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}