{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T04:57:43Z","timestamp":1781153863352,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the relationship between umbilical and renal artery Doppler indices in fetuses with growth restriction (FGR) and to examine their association with amniotic fluid index (AFI), early\u2010 and late\u2010onset subtypes, and perinatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective observational study included 151 singleton FGR pregnancies between 24 and 37\u2009weeks of gestation. Doppler measurements of the umbilical, middle cerebral, ductus venosus, and renal arteries were performed by a single perinatologist. Fetuses were classified into four groups according to umbilical artery (UA) flow pattern: normal resistance, increased resistance, absent end\u2010diastolic flow (AEDF), and reversed end\u2010diastolic flow (REDF). Associations between Doppler indices, AFI, and neonatal outcomes were analyzed using Spearman correlation, while group comparisons were performed with the Kruskal\u2013Wallis and Wilcoxon rank\u2010sum tests. Multivariable linear and logistic regression analyses were used to assess independent associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Renal artery pulsatility and resistance indices did not differ significantly among UA flow groups, whereas a modest decline in the systolic\/diastolic ratio was observed with increasing UA severity. Middle cerebral artery pulsatility index and cerebroplacental ratio decreased progressively, while ductus venosus pulsatility index increased across severity groups (all p\u2009&lt;\u20090.001). Renal Doppler indices were significantly lower in early\u2010onset FGR but showed no independent association with NICU admission or neonatal death after adjustment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Renal artery Doppler parameters provide complementary physiological insight into fetal hemodynamic adaptation in growth\u2010restricted pregnancies, particularly in early\u2010onset cases and those complicated by preeclampsia; however, their independent predictive value for neonatal outcomes appears limited.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jum.70183","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T13:13:36Z","timestamp":1769174016000},"page":"1455-1464","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Relationship Between Umbilical Artery Flow Parameters and Renal Artery Doppler Indices in Fetuses With Growth Restriction"],"prefix":"10.1002","volume":"45","author":[{"given":"Hale \u00d6zer","family":"\u00c7altek","sequence":"first","affiliation":[{"name":"Department of Perinatology Ba\u015fak\u015fehir \u00c7am and Sakura City Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Selvi","sequence":"additional","affiliation":[{"name":"Department of Perinatology Ba\u015fak\u015fehir \u00c7am and Sakura City Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ecem","family":"Ok\u015fen","sequence":"additional","affiliation":[{"name":"Department of Perinatology Ba\u015fak\u015fehir \u00c7am and Sakura City Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu\u011fba Nur \u00c7im","family":"\u00c7olak","sequence":"additional","affiliation":[{"name":"Department of Perinatology Ba\u015fak\u015fehir \u00c7am and Sakura City Hospital  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2582-7675","authenticated-orcid":false,"given":"Zeynep Kayao\u011flu","family":"Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[{"name":"Department of Perinatology Ba\u015fak\u015fehir \u00c7am and Sakura City Hospital  Istanbul 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