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We present a case series of three adolescents in whom high\u2010frequency cutaneous ultrasound was essential for the diagnosis, revealing homogeneous, hypoechoic, and non\u2010compressible dermal thickening around the proximal interphalangeal joints without evidence of synovitis, tendon involvement, or bone erosions. Ultrasound also enabled objective monitoring of treatment response following intralesional corticosteroid injections in two cases. Cutaneous ultrasound represents a valuable, non\u2010invasive tool for both the diagnosis and follow\u2010up of pachydermodactyly, avoiding unnecessary invasive procedures.<\/jats:p>","DOI":"10.1002\/jum.70187","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T12:43:46Z","timestamp":1770295426000},"page":"1517-1524","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasound Features and Therapeutic Monitoring of Pachydermodactyly"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3222-6550","authenticated-orcid":false,"given":"Sonia","family":"Romero\u2010Romero","sequence":"first","affiliation":[{"name":"Department of Dermatology Hospital Universitari Sagrat Cor, Grupo Hospitalario Quir\u00f3nsalud  Barcelona 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