{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T05:07:32Z","timestamp":1783832852850,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2026,8]]},"abstract":"\n Objectives<\/jats:title>\n To compare the application value of 4\u2010dimensional hysterosalpingo\u2010contrast sonography (4D\u2010HyCoSy) and x\u2010ray hysterosalpingography (HSG) in intrauterine insemination (IUI) patients.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In this retrospective study, a total of 725 infertile patients who underwent IUI in Ganzhou Maternal and Child Health Hospital from January 2023 to June 2024 were divided into 2 groups based on the type of salpingography: 535 cases in the HSG group and 190 cases in the 4D\u2010HyCoSy group. The clinical pregnancy rates, the number of IUI cycles required to achieve clinical pregnancy, and the incidence of adverse pregnancy outcomes were compared between the 2 groups.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n There were no significant differences in baseline data between the HSG group and the 4D\u2010HyCoSy group. The clinical pregnancy rates were 19.43% for the HSG group and 17.89% for the 4D\u2010HyCoSy group (\n p<\/jats:italic>\n \u2009=\u20090.66). The number of IUI cycles required to achieve clinical pregnancy was 1.55\u2009\u00b1\u20090.65 for the HSG group and 1.62\u2009\u00b1\u20090.79 for the 4D\u2010HyCoSy group (\n p<\/jats:italic>\n \u2009=\u20090.65). The ectopic pregnancy rates were 2.8% for the HSG group and 2.9% for the 4D\u2010HyCoSy group (\n p<\/jats:italic>\n \u2009=\u20090.43). The biochemical pregnancy rates were 1.9% for the HSG group and 1.6% for the 4D\u2010HyCoSy group (\n p<\/jats:italic>\n \u2009=\u20090.42). The early miscarriage rates were 11.5% for the HSG group and 14.7% for the 4D\u2010HyCoSy group (\n p<\/jats:italic>\n \u2009=\u20090.63). No significant differences were found in any of these parameters.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The type of salpingography HSG and 4D\u2010HyCoSy do not affect the clinical pregnancy outcomes in IUI. Therefore, it is recommended that HSG be phased out in favor of adopting 4D\u2010HyCoSy as the first\u2010line diagnostic test for tubal patency in pre\u2010IUI evaluation.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/jum.70213","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T08:40:50Z","timestamp":1772959250000},"page":"1655-1661","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of the Application Value of 4\u2010Dimensional Hysterosalpingo\u2010Contrast Sonography and X\u2010Ray Hysterosalpingography in Intrauterine Insemination"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1811-5367","authenticated-orcid":false,"given":"Yongyu","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Reproductive and Genetic Medicine Ganzhou Maternal and Child Health Hospital Ganzhou Jiangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefen","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Reproductive and Genetic Medicine Ganzhou Maternal and Child Health Hospital Ganzhou Jiangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Zuo","sequence":"additional","affiliation":[{"name":"Department of Physical Examination Ganzhou Maternal and Child Health Hospital Ganzhou Jiangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0362-4969","authenticated-orcid":false,"given":"Yun","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Reproductive and Genetic Medicine Ganzhou Maternal and Child Health Hospital Ganzhou Jiangxi 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