{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:02:09Z","timestamp":1789534929700,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Ultrasound\u2010guided puncture and lavage (UGPL) is an established first\u2010line therapy for chronic rotator cuff calcific tendinopathy (RCCT). However, insufficient treatment response remains common, and residual calcification may contribute to persistent tendinitis. This study examines tendon neovascularization assessed by power Doppler ultrasound (PDUS) following UGPL and evaluates its correlation with clinical symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty\u2010four patients with a single, large and dense calcific deposit underwent UGPL without steroid injection and were followed for 12\u2009months. Vascularization was quantified by PDUS using the Chiou Score and a novel Vascular Score. Patient\u2010reported outcomes included pain intensity (Pain NRS) and the subjective shoulder value (SSV). Associations between PDUS scores and outcomes were assessed using linear mixed\u2010effects models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Relevant PDUS signals (Chiou Score \u22652) were observed in 54% of patients at least once during the 12\u2010month follow\u2010up, without clustering at specific time points. Despite radiographic resolution in 70% of cases, residual calcifications remained detectable on ultrasound in all patients except 1. In the mixed\u2010effects models including all follow\u2010up events, PDUS scores were significantly associated with clinical symptoms. Higher Chiou and Vascular Scores corresponded to lower SSV values (Chiou Score: \u03b2\u2009=\u2009\u22125.91,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001; Vascular Score: \u03b2\u2009=\u2009\u22123.12,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) and higher Pain NRS values (Chiou Score: \u03b2\u2009=\u20090.67,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.001; Vascular Score: \u03b2\u2009=\u20090.34,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt; .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Persistent tendon hypervascularization correlates with worse outcomes after UGPL, despite radiographic resolution. These findings support the concept of postinterventional \u201cmicrocalcific associated tendinopathy\u201d and highlight the potential of PDUS as a monitoring tool in the management of RCCT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jum.70298","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T12:10:14Z","timestamp":1783599014000},"page":"2213-2226","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Power Doppler Ultrasound After Ultrasound\u2010Guided Lavage of Rotator Cuff Calcific Tendinopathy: Association With Clinical Outcomes"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9164-0545","authenticated-orcid":false,"given":"Stefan","family":"Diermayr","sequence":"first","affiliation":[{"name":"Department of Rheumatology Schulthess Klinik  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Despont","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Schulthess Klinik  Switzerland"},{"name":"Surgical Outcome Research Center University Hospital Basel  Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Brune","sequence":"additional","affiliation":[{"name":"Research and Development Schulthess Klinik  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Etter","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Schulthess Klinik  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Scheibel","sequence":"additional","affiliation":[{"name":"Shoulder and Elbow Surgery Schulthess Klinik  Zurich Switzerland"},{"name":"Department of Shoulder and Elbow Surgery, Center for Musculoskeletal Surgery Charit\u00e8 Medicine University  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Forster","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Schulthess Klinik  Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asimina","family":"Lazaridou","sequence":"additional","affiliation":[{"name":"Research and Development Schulthess Klinik  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Audige","sequence":"additional","affiliation":[{"name":"Surgical Outcome Research Center University Hospital Basel  Basel Switzerland"},{"name":"Research and Development Schulthess Klinik  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1333941"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2015.02.024"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-10-95"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-199707000-00001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14933"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2009.07.008"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513487066"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4224-7"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-06669-0"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2017162888"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-020-07334-2"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2018-214971"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2023-076447"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.O.00417"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(01)00353-2"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2010.01.012"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2002.21.3.289"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.715423"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2007.02.123"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1995.14.1.7"},{"key":"e_1_2_7_22_1","first-page":"284","article-title":"Calcific 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