{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T17:12:22Z","timestamp":1791047542925,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T00:00:00Z","timestamp":1786233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T00:00:00Z","timestamp":1786233600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe the role of high\u2010frequency ultrasound (HFUS) in the anatomical evaluation and monitoring of female genital rejuvenation procedures and to illustrate characteristic sonographic patterns associated with commonly used aesthetic treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective observational study reviewed anonymized clinical and ultrasound records from eight female patients who underwent genital rejuvenation in a private dermatologic ultrasound center. HFUS examinations were performed using 20\u201333\u2009MHz linear probes in standardized B\u2010mode, with color Doppler added when indicated. Representative cases were selected to demonstrate normal anatomy, age\u2010related changes, postprocedural findings, and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>HFUS provided high\u2010resolution visualization of the epidermis, dermis, subcutaneous tissue, and fascial planes of the external genitalia. Younger patients showed compact fat lobules and well\u2010defined fascial layers, whereas older patients exhibited dermal thinning and a subepidermal low\u2010echogenicity band. Postprocedural HFUS identified distinct patterns for each treatment modality, including anechoic lobulated deposits after hyaluronic acid, hyperechoic punctate \u201csnowfall\u201d reflections after calcium hydroxyapatite, linear hyperechoic structures after absorbable threads, and focal hyperechoic panniculitis following lipolytic mesotherapy. HFUS also aided in detecting and characterizing treatment\u2010related changes and potential complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>HFUS appears to be a useful adjunct for minimally invasive female genital rejuvenation, enabling detailed anatomical assessment, visualization of injected materials, and monitoring of treatment\u2010related changes. These preliminary findings support the integration of HFUS into aesthetic practice and highlight the need for further studies to standardize its application in this growing field.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jum.70306","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T02:27:03Z","timestamp":1786328823000},"page":"2251-2259","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["High\u2010Frequency Ultrasound Assessment of Female Genital Rejuvenation"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5229-8596","authenticated-orcid":false,"given":"Luciana","family":"Zattar","sequence":"first","affiliation":[{"name":"Hospital S\u00edrio\u2010Liban\u00eas  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5477-1964","authenticated-orcid":false,"given":"Nat\u00e1lia","family":"Venturelli Marques de Souza","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Venturelli  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-013-0211-4"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003617"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.5070\/D3249041410"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-023-03617-3"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.46971\/ausbid.1167911"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000002418"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S416232"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.70074"},{"key":"e_1_2_9_10_1","first-page":"1","article-title":"PDO threads, calcium hydroxyapatite, and l\u2010polylactic acid for vulvar flaccidity \u2010 indications, technique, and results","volume":"15","author":"Carvalho AV","year":"2023","journal-title":"Surg Cosmet Dermatology."},{"key":"e_1_2_9_11_1","article-title":"A novel hyaluronic acid filling technique for restoring volume of the labia majora","volume":"15","author":"Tarabini F","year":"2023","journal-title":"Cureus."},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.15080"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12329"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics15050627"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13233512"},{"key":"e_1_2_9_16_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1590\/0100-3984.2024.57.e7-en","article-title":"Advancements in dermatologic ultrasound and its use in facial aesthetic interventions","volume":"57","author":"Oliveira ALK","year":"2024","journal-title":"Radiol Bras."},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1590\/0100-3984.2024.0035"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2025.05.1428"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.6719"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14032"},{"key":"e_1_2_9_21_1","first-page":"251","article-title":"Ultrasound in aesthetics: filler and non\u2010filler applications","volume":"45","author":"Cavallieri FA","year":"2024","journal-title":"Semin Ultrasound, CT MRI."},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13050970"},{"key":"e_1_2_9_23_1","first-page":"57","article-title":"Ultrasonographic subepidermal low\u2010echogenic band, dependence of age and body site","volume":"10","author":"Sandby\u2010M\u00f8ller J","year":"2004","journal-title":"Ski Res Technol Off J Int Soc Bioeng Ski [and] Int Soc Digit Imaging Ski [and] Int Soc Ski 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