{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:02:09Z","timestamp":1789534929333,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study represents the first evaluation of the Plaque\u2010RADS (Reporting and Data System)\u00a0classification system's applicability in carotid ultrasound examinations. It focuses on analyzing inter\u2010observer and intra\u2010observer agreement among physicians of varying experience levels while investigating its learning curve to validate the system's suitability and stability within the ultrasound field.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center study consecutively enrolled 604 carotid ultrasound images from 302 examinees. Three sonographers with varying levels of experience (expert, associate senior physician, and intermediate physician) independently classified all images using the Plaque\u2010RADS system to assess inter\u2010observer agreement. A second assessment was conducted 3\u2009months after the initial evaluation to examine intra\u2010observer agreement. Moreover, learning curves for each physician level were evaluated using 5 consecutive case groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Regarding inter\u2010observer agreement, near\u2010perfect agreement was observed between the expert and associate senior physician (\u03ba\u2009=\u20090.804, 95% CI: 0.765\u20130.842). Agreement between the expert and intermediate physician (\u03ba\u2009=\u20090.754, 95% CI: 0.711\u20130.793) and between the associate senior and intermediate physician (\u03ba\u2009=\u20090.670, 95% CI: 0.620\u20130.713) was also statistically significant. Intra\u2010observer agreement demonstrated good stability across 2 assessments for all 3 physicians, with \u03ba values of 0.901 (95% CI: 0.872\u20130.930) (expert), 0.843 (95% CI: 0.808\u20130.878) (associate senior physician), and 0.804 (95% CI: 0.766\u20130.843) (intermediate physician). Learning curve analysis revealed that both associate senior physician and intermediate physician steadily improved their agreement with the expert as case experience increased.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Research findings indicate that the Plaque\u2010RADS classification system demonstrates high applicability in the field of ultrasound. Through training, this system can be effectively utilized by physicians of varying skill levels, providing a reliable tool for standardized assessment of carotid plaque and stroke risk stratification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jum.70311","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T17:05:32Z","timestamp":1780679132000},"page":"2283-2297","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Application of the Carotid Plaque\u2010\n                    <scp>RADS<\/scp>\n                    Classification System in Ultrasound"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0921-5204","authenticated-orcid":false,"given":"Jing","family":"Dai","sequence":"first","affiliation":[{"name":"Health Management Medicine Department Inner Mongolia People's Hospital  Hohhot China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Mei","sequence":"additional","affiliation":[{"name":"Health Management Medicine Department Inner Mongolia People's Hospital  Hohhot China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufang","family":"Wang","sequence":"additional","affiliation":[{"name":"Health Management Medicine Department Inner Mongolia People's Hospital  Hohhot China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Dai","sequence":"additional","affiliation":[{"name":"First Clinical Medical College, Jiangxi Medical College Nanchang University  Nanchang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Risu","family":"Na","sequence":"additional","affiliation":[{"name":"Health Management Medicine Department Inner Mongolia People's Hospital  Hohhot China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00642-1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0000000000000410"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0312013"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-025-01859-y"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2025.05.014"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.121.035692"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.11152\/mu-3190"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.RV17044"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2024.05.001"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.030739"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.706490"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2023.09.005"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A8769"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2024.07.011"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.02.082"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.483024"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2015.09.007"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.03.002"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics8040069"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultras.2021.106599"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.16150"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-021-00963-9"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2021.102201"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwac141"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2020.04.021"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.70311","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.70311","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.70311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:05:05Z","timestamp":1789531505000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.70311"}},"subtitle":["Inter\u2010 and Intra\u2010Observer Agreement Analysis and Learning Curve Analysis"],"short-title":[],"issued":{"date-parts":[[2026,6,5]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/jum.70311"],"URL":"https:\/\/doi.org\/10.1002\/jum.70311","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,5]]},"assertion":[{"value":"2026-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}