{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T04:37:46Z","timestamp":1792643866811,"version":"4.5.0"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To investigate the contribution of rapid on\u2010site evaluation (ROSE) to the diagnostic accuracy of ultrasound\u2010guided fine\u2010needle aspiration biopsy (FNAB) in parotid gland lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this single\u2010center retrospective study, 589 parotid gland lesions evaluated between January 2012 and September 2022 were included. All procedures were performed under ultrasound guidance by interventional radiologists with more than 15\u2009years of experience, using 20\u2010gauge fine\u2010needle aspiration needles. ROSE was performed by a cytopathologist with more than 20\u2009years of experience. Cytological results were classified as diagnostic, suspicious, indeterminate, or non\u2010diagnostic. For patients who underwent surgery, postoperative histopathological diagnoses were compared with cytopathological findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 589 lesions, 504 (85.6%) were benign and 85 (14.4%) were malignant. The most common benign lesions were Warthin tumor (33.6%) and pleomorphic adenoma (26.1%). FNAB results were diagnostic in 541 lesions (91.9%), suspicious in 38 (6.5%), indeterminate in 8 (1.4%), and non\u2010diagnostic in only 2 (0.3%). Among the 284 patients who underwent surgical resection, ROSE\u2010guided FNAB cytology was concordant with postoperative histopathology in 278 (97.9%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ROSE\u2010guided FNAB represents a highly accurate, minimally invasive diagnostic strategy for parotid gland lesions, yielding definitive cytological results in a single procedure while substantially reducing the need for repeat sampling or more invasive diagnostic approaches.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jum.70520","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:37:58Z","timestamp":1792640278000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rapid On\u2010Site Evaluation in Ultrasound\u2010Guided Fine\u2010Needle Aspiration Biopsy of Parotid Gland Lesions"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2820-1384","authenticated-orcid":false,"given":"Kaz\u0131m Burak","family":"Karaca","sequence":"first","affiliation":[{"name":"Department of Radiology Tokat State Hospital  Tokat Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5238-8911","authenticated-orcid":false,"given":"Yavuz","family":"Metin","sequence":"additional","affiliation":[{"name":"Department of Radiology Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koray","family":"Ceyhan","sequence":"additional","affiliation":[{"name":"Department of Pathology Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evren","family":"\u00dcst\u00fcner","sequence":"additional","affiliation":[{"name":"Department of Radiology Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4548-9693","authenticated-orcid":false,"given":"Nam\u0131k Kemal","family":"Alt\u0131nba\u015f","sequence":"additional","affiliation":[{"name":"Department of Radiology Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cemil","family":"Ya\u011fc\u0131","sequence":"additional","affiliation":[{"name":"Department of Radiology Ankara University Faculty of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.bjoms.2022.11.281","article-title":"Salivary gland tumours: an epidemiological review of non\u2010neoplastic and neoplastic pathology","volume":"61","author":"McKenzie J","year":"2023","journal-title":"Br J Oral Maxillofac Surg"},{"key":"e_1_2_7_3_1","article-title":"Role of fine needle aspiration in malignant parotid tumors at a single\u2010center experience: a retrospective cohort study","volume":"64","author":"Alwagdani A","year":"2021","journal-title":"Ann Med Surg (Lond)"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1177\/0194599815607841","article-title":"Sensitivity, specificity, and posttest probability of parotid fine\u2010needle aspiration: a systematic review and meta\u2010analysis","volume":"154","author":"Liu CC","year":"2016","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"NP340","DOI":"10.1177\/01455613211058922","article-title":"Clinical diagnostic utility of ultrasound\u2010guided fine needle aspiration biopsy in parotid masses","volume":"103","author":"Hamour AF","year":"2024","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/cyt.12811","article-title":"A retrospective comparison of salivary gland fine needle aspiration reporting with the Milan system for reporting salivary gland cytology","volume":"31","author":"Mullen D","year":"2020","journal-title":"Cytopathology"},{"key":"e_1_2_7_7_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjoto.2020.102590","article-title":"The role of fine needle aspiration biopsy in deep lobe parotid tumors: comparison of preoperative cytology and postoperative histopathologic results","volume":"42","author":"Seyhun N","year":"2021","journal-title":"Am J Otolaryngol"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1309\/AJCPOIE0CZNAT6SQ","article-title":"A systematic review and meta\u2010analysis of the diagnostic accuracy of fine needle aspiration cytology for parotid gland lesions","volume":"136","author":"Schmidt RL","year":"2011","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/s43163-021-00096-8","article-title":"Role of FNAC in diagnosis of parotid lesions","volume":"37","author":"Youssef A","year":"2021","journal-title":"Egypt J Otolaryngol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1309\/AJCPEGZMJKC42VUP","article-title":"The influence of rapid onsite evaluation on the adequacy rate of fine\u2010needle aspiration cytology: a systematic review and meta\u2010analysis","volume":"139","author":"Schmidt RL","year":"2013","journal-title":"Am J Clin Pathol"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/cyt.12428","article-title":"Agreement between rapid on\u2010site evaluation and the final cytological diagnosis of salivary gland specimens","volume":"28","author":"Wangsiricharoen S","year":"2017","journal-title":"Cytopathology"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1007\/s00405-020-05868-1","article-title":"The role of fine\u2010needle aspiration biopsy (FNAB) in the diagnostic management of parotid gland masses with emphasis on potential pitfalls","volume":"277","author":"Dostalova L","year":"2020","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"e_1_2_7_13_1","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1002\/hed.23193","article-title":"Comparison of ultrasound\u2010guided core biopsy versus fine\u2010needle aspiration biopsy in the evaluation of salivary gland lesions","volume":"35","author":"Douville NJ","year":"2013","journal-title":"Head Neck"},{"key":"e_1_2_7_14_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2025.112532","article-title":"Fine\u2010needle aspiration or core needle biopsy? A meta\u2010analysis of diagnostic accuracy and procedural outcomes in salivary gland tumors","volume":"194","author":"Kassem K","year":"2026","journal-title":"Eur J Radiol"},{"key":"e_1_2_7_15_1","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1007\/s00405-018-5131-0","article-title":"Preoperative diagnostic of parotid gland neoplasms: fine\u2010needle aspiration cytology or core needle biopsy?","volume":"275","author":"Zbaren P","year":"2018","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"e_1_2_7_16_1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.mpdhp.2023.06.001","article-title":"Rapid on\u2010site evaluation for head and neck lesions","volume":"29","author":"De Oliveira GR","year":"2023","journal-title":"Diagn Histopathol"},{"key":"e_1_2_7_17_1","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s11845-015-1352-z","article-title":"Adequacy and accuracy of salivary gland fine needle aspiration cytology","volume":"185","author":"Mohammed Nur M","year":"2016","journal-title":"Ir J Med Sci"},{"key":"e_1_2_7_18_1","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1308\/003588413X13511609958370","article-title":"The diagnostic value of fine needle aspiration in parotid lumps","volume":"95","author":"Mallon DH","year":"2013","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1309\/AJCPMII6OSD2HSJA","article-title":"Salivary gland tumor fine\u2010needle aspiration cytology: a proposal for a risk stratification classification","volume":"143","author":"Griffith CC","year":"2015","journal-title":"Am J Clin Pathol"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.70520","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jum.70520","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jum.70520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:38:02Z","timestamp":1792640282000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jum.70520"}},"subtitle":["A Decade of Experience"],"short-title":[],"issued":{"date-parts":[[2026,10,21]]},"references-count":18,"alternative-id":["10.1002\/jum.70520"],"URL":"https:\/\/doi.org\/10.1002\/jum.70520","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,21]]},"assertion":[{"value":"2026-04-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"jum.70520"}}