{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T01:59:59Z","timestamp":1755223199418,"version":"3.43.0"},"reference-count":57,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T00:00:00Z","timestamp":1723680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002538"],"award-info":[{"award-number":["UL1TR002538"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["JEADV Clinical Practice"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lifestyle has been associated with acne, but few studies assess how the relationship changes over time. Observational studies often overlook the effects of acne medication use and participant age in relationships with lifestyle\u2010related factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe relationships between lifestyle\u2010related factors, medication use, and age in adolescent and young adult acne patients and acne\u2010free controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective study recruited 12\u2010 to 24\u2010year\u2010olds with or without acne at baseline. Surveys were electronically administered at enrolment and again 6 weeks later. Analyses were conducted on all participants who had complete baseline data (<jats:italic>N<\/jats:italic>\u2009=\u2009190) and participants who had complete baseline and follow\u2010up data (<jats:italic>N<\/jats:italic>\u2009=\u200961).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 190 participants who completed the baseline survey, ages ranged from 12 to 24 years, but acne cases were concentrated in the middle of this range while controls had comparably more participants with ages towards the extremes. Among 61 participants who completed both baseline and follow\u2010up surveys, no participants indicated worse acne over the 6 weeks, and most acne cases believed their acne improved (<jats:italic>n<\/jats:italic>\u2009=\u200925 [69.4%]). Acne cases who used medication daily (<jats:italic>N<\/jats:italic>\u2009=\u200924) saw improved emotion\u2010related quality of life between the two assessments (mean\u2009\u00b1\u2009standard deviation: 43.4\u2009\u00b1\u200924.4 to 29.1\u2009\u00b1\u200923.7; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Among acne cases who used medication daily, average fruit or vegetable consumption increased from 2.4\u2009\u00b1\u20092.0 to 3.0\u2009\u00b1\u20092.9 times per day over the preceding 7 days (<jats:italic>p<\/jats:italic>\u2009=\u20090.02). Among acne cases who believed their acne improved over the 6 weeks post\u2010dermatology visit (<jats:italic>N<\/jats:italic>\u2009=\u200925), average days of skin picking over the previous 7 days declined between assessments (3.9\u2009\u00b1\u20092.4 to 2.4\u2009\u00b1\u20091.9 days; <jats:italic>p<\/jats:italic>\u2009=\u20090.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Medication use and age differences should be considered when designing future studies on acne and lifestyle\u2010related factors.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jvc2.521","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T12:38:36Z","timestamp":1723725516000},"page":"82-94","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lifestyle, medication use, and age considerations with acne vulgaris: A prospective study"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1980-2092","authenticated-orcid":false,"given":"Ashley M.","family":"Snyder","sequence":"first","affiliation":[{"name":"Department of Dermatology University of Utah Salt Lake City Utah USA"},{"name":"Department of Population Health Sciences University of Utah Salt Lake City Utah USA"},{"name":"Division of Epidemiology, Department of Internal Medicine University of Utah Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1697-1659","authenticated-orcid":false,"given":"Caroline J.","family":"Stone","sequence":"additional","affiliation":[{"name":"School of Medicine University of Utah Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-7308-213X","authenticated-orcid":false,"given":"Nicole","family":"Ufkes","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Utah Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Greene","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences University of Utah Salt Lake City Utah USA"},{"name":"Division of Epidemiology, Department of Internal Medicine University of Utah Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary C.","family":"Playdon","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences University of Utah Salt Lake City Utah USA"},{"name":"Department of Nutrition &amp; Integrative Physiology University of Utah Salt Lake City Utah USA"},{"name":"Cancer Control and Population Sciences, Huntsman Cancer Institute University of Utah Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maureen A.","family":"Murtaugh","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences University of Utah Salt Lake City Utah USA"},{"name":"Division of Epidemiology, Department of Internal Medicine University of Utah Salt Lake City Utah USA"},{"name":"Department of Nutrition &amp; Integrative Physiology University of Utah Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan E.","family":"Vanneman","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences University of Utah Salt Lake City Utah USA"},{"name":"Division of Epidemiology, Department of Internal Medicine University of Utah Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9297-0941","authenticated-orcid":false,"given":"Aaron M.","family":"Secrest","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Utah Salt Lake City Utah USA"},{"name":"Department of Population Health Sciences University of Utah Salt Lake City Utah USA"},{"name":"Department of Dermatology Christchurch Hospital, Health New Zealand Te Whatu Ora Christchurch New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-021-02826-1"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494812454235"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.04.015"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15204"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu10081049"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12673"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijdvl.IJDVL_109_17"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1346"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jand.2018.02.009"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu2101060"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2007.11.005"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/86.1.107"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.01.046"},{"issue":"1","key":"e_1_2_10_15_1","first-page":"11","article-title":"The relation of life stress and emotions to human sebum secretion and to the mechanism of acne vulgaris","volume":"41","author":"Lorenz TH","year":"1953","journal-title":"J Lab Clin Med"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13384"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.02.040"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14227"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)60130-7"},{"issue":"4","key":"e_1_2_10_20_1","first-page":"359","article-title":"Necropsies on Okinawans; 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