{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:15:54Z","timestamp":1791486954991,"version":"4.3.4"},"reference-count":14,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T00:00:00Z","timestamp":1551916800000},"content-version":"vor","delay-in-days":65,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["NSC 105\u20102314\u2010B\u2010182\u2010024\u2010MY3"],"award-info":[{"award-number":["NSC 105\u20102314\u2010B\u2010182\u2010024\u2010MY3"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Kaohsiung J of Med Scie"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p>Renal epithelioid angiomyolipoma (eAML) is considered a malignant variant of angiomyolipoma (AML). From 2001 to 2016, a total of 570 patients were diagnosed with renal AML in Linko Chang Gung Memorial Hospital, Taiwan, including 23 cases of renal eAML. All 23 eAML cases were made up of at least 10% of epithelioid cells histologically. Three of these cases were found with multiple tumors. Two cases developed distant metastasis: one had mediastinal lymph nodes and bilateral lung metastasis; the other one had tumor recurrence over liver and retroperitoneum 1\u2009year after radical nephrectomy. They were then divided into invasive (n\u2009=\u20095) and noninvasive (n\u2009=\u200918) groups according to their clinical behavior. The invasive group showed more severe nuclear atypia and higher rates in tumor necrosis. There was statistically no significance in relation to a patient's age, tumor size, and mitotic count between two groups. After conducting a series of studies, we suggest treating eAML with the guideline of renal cell carcinoma.<\/jats:p>","DOI":"10.1002\/kjm2.12006","type":"journal-article","created":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T14:12:34Z","timestamp":1551967954000},"page":"33-38","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinicopathologic analysis of renal epithelioid angiomyolipoma: Consecutively excised 23 cases"],"prefix":"10.1002","volume":"35","author":[{"given":"Han\u2010Yu","family":"Tsai","sequence":"first","affiliation":[{"name":"Division of Urology, Department of Surgery Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun\u2010Han","family":"Lee","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwai\u2010Fong","family":"Ng","sequence":"additional","affiliation":[{"name":"Division of Pathology Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Ting","family":"Kao","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Keng","family":"Chuang","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery Chang Gung Memorial Hospital  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31817ed7a6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-007-0509-1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-015-0700-9"},{"key":"e_1_2_7_5_1","first-page":"1180","article-title":"A case of renal angiomyolipoma with intracardiac extension and asymptomatic pulmonary embolism","volume":"6","author":"Li X","year":"2013","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"E564","DOI":"10.5489\/cuaj.1814","article-title":"Malignant epithelioid angiomyolipoma invading the inferior vena cava: Using a temporary vena cava filter to prevent tumour emboli during nephrectomy","volume":"8","author":"Li X","year":"2014","journal-title":"Can Urol Assoc J"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318206f2a9"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181d90370"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kjms.2010.05.003"},{"key":"e_1_2_7_10_1","first-page":"823","article-title":"Comprehensive clinical and pathological analysis of aggressive renal epithelioid angiomyolipoma: Report of three cases","volume":"7","author":"Luo J","year":"2014","journal-title":"Onco Targets Ther"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyr035"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-017-1629-4"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2016.11.001"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.274065147"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10396-016-0705-1"}],"container-title":["The Kaohsiung Journal of Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fkjm2.12006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/kjm2.12006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T07:35:31Z","timestamp":1694676931000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/kjm2.12006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1002\/kjm2.12006"],"URL":"https:\/\/doi.org\/10.1002\/kjm2.12006","archive":["Portico"],"relation":{},"ISSN":["1607-551X","2410-8650"],"issn-type":[{"value":"1607-551X","type":"print"},{"value":"2410-8650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"2018-02-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}